Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer-related mortality globally. The American Cancer Society …

Simple Summary Worldwide gastrointestinal (GI) malignancies account for about 25% of the
global cancer incidence. For some malignancies, screening programs, such as routine colon …

Colorectal cancer (CRC) is one of the most prevalent and deadly malignancies that can be
influenced by Fusobacterium nucleatum (Fn), a bacterium that promotes tumor development …

Background Chronic subdural hematoma (CSDH) is a common neurological disease, and
the surgical evacuation of subdural collection remains the primary treatment approach for …

Colorectal cancer (CRC) is a common and deadly cancer worldwide with a high lethality
rate. Disulfidptosis has been found to be an emerging mode of death in cancer, and the …

Background: In recent years, liquid biopsy has shown great potential for improving cancer
diagnosis and treatment. This study aimed to explore the trends and prospects in liquid …

Introduction The number of umbrella reviews (URs) that compiled systematic reviews and
meta-analysis (SR-MAs) has increased dramatically over recent years. No formal guidance …

Background and aims The gut microbiota is implicated in the pathogenesis of colorectal
cancer (CRC). We aimed to map the CRC mucosal microbiota and metabolome and define …

Background This open-label, multicentre, phase II/III trial assessed the noninferiority of
trifluridine/tipiracil (FTD/TPI) plus bevacizumab vs. fluoropyrimidine and irinotecan plus …

Background The validity of observational studies and their meta-analyses is contested.
Here, we aimed to appraise thousands of meta-analyses of observational studies using a …