Despite improved hematologic care, multiendocrine dysfunction is a common complication
of homozygous transfusion-dependent β-thalassemia. In this study our goal was to estimate …

Background: Iron overload is an important issue in the state of thalassemic patients due to
the harmful effect of high concentration of iron deposited in different tissues in human body …

Objective To determine the prevalence of growth abnormality and endocrine dysfunction in a
group of multi transfused thalassemic children and to correlate these with their body iron …

Endocrine Abnormalities in β-thalassemia major are common disturbing complications, that
need prompt management. Importance of this work was to evaluate the some biochemical …

Background Severe iron overload due to recurrent transfusions for chronic anemia and
inadequate iron chelation therapy in thalassemia major patients result in various …

Thalassemia is the most common genetic disorder worldwide1. The striking increase in
survival of these patients over the past decade has focused attention on abnormal endocrine …

Abstract β-thalassemia is an inherited hemoglobin disorder. It is considered as a health
problem in Palestine thus, premarital screening for thalassemia became compulsory. The …

This study was carried out to determine ghost membrane Ca “ATPase activity in the infected
erythrocytes as a correlate of intraerythrocytic Ca “content, parasite maturation and age. In …

Background High plasma iron in β-thalassemia major (BTM) leads to enhanced generation
of reactive oxygen species, oxidative stress, and endocrine disorders. We aimed to assess …

With modern treatment approaches in patients with thalassemia major, the life expectancy
and quality of life of patients have increased, but chronic hypoxia, anemia and endocrine …