Paediatric melanoma

C Stefanaki, L Chardalias, E Soura… - Journal of the …, 2017 - Wiley Online Library
Paediatric melanoma, although rare, is the most common skin cancer in children. Our
current knowledge on paediatric melanoma incidence trends is expanding, as several …

The pathology of melanoma

CJ Cockerell - Dermatologic clinics, 2012 - Elsevier
Although melanoma represents only 10% of all skin cancer diagnoses, it accounts for at
least 65% of all skin cancer–related deaths. The number of new cutaneous melanoma cases …

The unique clinical characteristics of melanoma diagnosed in children

D Han, JS Zager, G Han, SS Marzban… - Annals of surgical …, 2012 - Springer
Background Studies have demonstrated a higher rate of nodal metastases in melanoma of
childhood, but there is controversy about the overall prognosis relative to adults. We …

Melanoma in children and adolescents: analysis of susceptibility genes in 123 Italian patients

C Pellegrini, S Raimondi, L Di Nardo… - Journal of the …, 2022 - Wiley Online Library
Background A polygenic inheritance involving high, medium and low penetrance genes has
been suggested for melanoma susceptibility in adults, but genetic information is scarce for …

Mitotically active proliferative nodule arising in a giant congenital melanocytic nevus: a diagnostic pitfall

TLT Nguyen, A Theos, DR Kelly, K Busam… - The American Journal …, 2013 - journals.lww.com
Proliferative (cellular) nodules (PN) which mimic malignant melanoma clinically and
histologically are described in congenital melanocytic nevi (CMN) and may pose significant …

Spitzoid and non‐spitzoid melanoma in children. A prognostic comparative study

S Paradela, E Fonseca… - Journal of the …, 2013 - Wiley Online Library
Background Spitzoid melanoma is a rare melanoma subtype often developing in children
with unknown biological potential. Objectives To compare the clinical and histopathological …

The challenge of melanocytic lesions in pediatric patients: clinical-pathological findings and the diagnostic value of PRAME

GR Umano, ME Errico, V D'Onofrio, G Delehaye… - Frontiers in …, 2021 - frontiersin.org
Pediatric melanoma is a rare disease especially in children aged younger than 10 years old.
Recent estimates report a rise of disease incidence in both adults and children. Diagnostic …

PRAME immunohistochemical expression and TERT promoter mutational analysis as ancillary diagnostic tools for differentiating proliferative nodules from melanoma …

A Boutko, M Hagstrom, N Lampley, A Roth… - The American Journal …, 2023 - journals.lww.com
Proliferative nodules (PNs) are benign melanocytic proliferations that typically develop
within congenital melanocytic nevi. These tumors have overlapping histological features …

Controversies in the evaluation and management of atypical melanocytic proliferations in children, adolescents, and young adults

D Reed, R Kudchadkar, JS Zager, VK Sondak… - Journal of the National …, 2013 - jnccn.org
The rising incidence of melanoma in children has brought increased attention to the clinical
and pathologic diagnosis of pigmented lesions in the pediatric age group. Although …

Fluorescence in situ hybridization analysis of atypical melanocytic proliferations and melanoma in young patients

EH DeMarchis, SM Swetter, CD Jennings… - Pediatric …, 2014 - Wiley Online Library
Morphologic heterogeneity among melanocytic proliferations is a common challenge in the
diagnosis of melanoma. In particular, atypical melanocytic lesions in children, adolescents …