Infection and inflammation account for approximately 25% of cancer-causing factors.
Inflammation-related cancers are characterized by mutagenic DNA lesions, such as 8-oxo-7 …

The incidence of cholangiocarcinoma (CCA) has been increasing over the past few years.
Although there are surgery, chemotherapy and other conventional treatment methods, the …

Septic cardiomyopathy is associated with mitochondrial damage and endoplasmic reticulum
(ER) dysfunction. However, the upstream mediator of mitochondrial injury and ER stress has …

Mitochondrial fusion is linked to heart and liver ischemia‐reperfusion (IR) insult.
Unfortunately, there is no report to elucidate the detailed influence of mitochondrial fusion in …

The basic pathophysiological mechanisms underlying septic cardiomyopathy have not yet
been completely clarified. Disease-specific treatments are lacking, and care is still based on …

Hepatocyte nuclear factor 4 alpha (HNF4α) is critical for hepatic differentiation. Recent
studies have highlighted its role in inhibition of hepatocyte proliferation and tumor …

Chronic obstructive pulmonary disease is a complex condition with multiple etiologies,
including inflammation. We identified a novel long noncoding RNA (lncRNA), interleukin 6 …

Despite significant advances in therapies in past decades, the mortality rate of septic
cardiomyopathy remains high. The aim of this study is to explore the therapeutic effects of …

Mitochondria are double-membrane organelles that provide the majority of a cell's energy.
Furthermore, mitochondria are involved in various cellular biological activities, including …

Natural products have offered a number of exciting approaches in cancer treatment over the
years. In this study, we investigated the prophylactic and therapeutic effects of the …