[HTML][HTML] Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery

A Malek-Khatabi, MS Razavi, A Abdollahi… - Biomaterials …, 2023 - pubs.rsc.org
Microneedles (MNs) have recently been found to have applications in drug, vitamin, protein
and vaccine delivery. Polymeric MN arrays continue to attract increasing attention due to …

Natural polysaccharide-based biodegradable polymeric platforms for transdermal drug delivery system: A critical analysis

S Noreen, JX Ma, M Saeed, F Pervaiz, MF Hanif… - Drug Delivery and …, 2022 - Springer
Natural biodegradable polymers generally include polysaccharides (starch, alginate,
chitin/chitosan, hyaluronic acid derivatives, etc.) and proteins (collagen, gelatin, fibrin, etc.) …

A comprehensive review of nanosuspension loaded microneedles: fabrication methods, applications, and recent developments

JG Vitore, S Pagar, N Singh, B Karunakaran… - Journal of …, 2023 - Springer
Abstract Background Nanosuspension-loaded microneedles (MNs) are an emerging and
advanced strategy used extensively to formulate lipophilic molecules by embedding them …

Smart fluorescent polysaccharides: Recent developments and applications

DC Novo, KJ Edgar - Carbohydrate Polymers, 2024 - Elsevier
Polysaccharides are ubiquitous, generally benign in nature, and compatible with many
tissues in biomedical situations, making them appealing candidates for new materials such …

Fabrication of polymeric microneedles using novel vacuum compression molding technique for transdermal drug delivery

SM Kshirsagar, T Kipping, AK Banga - Pharmaceutical Research, 2022 - Springer
Purpose To demonstrate the feasibility of vacuum compression molding as a novel
technique for fabricating polymeric poly (D, L-lactic-co-glycolic acid) microneedles. Methods …

Weibull β value for the discernment of drug release mechanism of PLGA particles

U de Jesús Martín-Camacho… - International Journal of …, 2023 - Elsevier
Mathematical models are used to characterize and optimize drug release in drug delivery
systems (DDS). One of the most widely used DDS is the poly (lactic-co-glycolic acid)(PLGA) …

Potential of microneedle systems for COVID-19 vaccination: current trends and challenges

J Hassan, C Haigh, T Ahmed, MJ Uddin, DB Das - Pharmaceutics, 2022 - mdpi.com
To prevent the coronavirus disease 2019 (COVID-19) pandemic and aid restoration to
prepandemic normality, global mass vaccination is urgently needed. Inducing herd immunity …

Polymer coated polymeric (PCP) microneedles for controlled delivery of drugs (dermal and intravitreal)

D Jakka, AV Matadh, VK Shankar… - Journal of …, 2022 - Elsevier
Microneedles are used to deliver drugs topically across the skin and mucous membranes.
Dissolvable microneedles are made using soluble polymers, which disintegrates in the …