Golden standard or obsolete method? Review of ECG applications in clinical and experimental context

T Stracina, M Ronzhina, R Redina… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular system and its functions under both physiological and pathophysiological
conditions have been studied for centuries. One of the most important steps in the …

Adult zebrafish as advanced models of human disease

RM White, EE Patton - Disease Models & Mechanisms, 2023 - journals.biologists.com
Modelling adult diseases to understand their aetiology and progression, and to develop new
therapies, is a major challenge for medical biology. We are excited by new efforts in the …

Sharing resources to advance translational research

KM Hooper, J Hmeljak - Disease Models & Mechanisms, 2022 - journals.biologists.com
The publication of Resource articles is essential for the dissemination of novel, or
substantially enhanced, tools, techniques, disease models, datasets and resources. By …

The effect of hypothermia and osmotic shock on the electrocardiogram of adult zebrafish

E Arel, L Rolland, J Thireau, AG Torrente, E Bechard… - Biology, 2022 - mdpi.com
Simple Summary Assessing cardiac toxicity of new drugs is a requirement for their approval.
One of the parameters which is carefully looked at is the QT interval, which is determined …

Disease Models & Mechanisms helps move heart failure to heart success

K Hooper, J Hmeljak - Disease Models & Mechanisms, 2022 - journals.biologists.com
Heart failure affects∼ 64 million people worldwide, resulting in high morbidity, mortality and
societal cost. Current treatment strategies are primarily geared at slowing the progression to …

Characterization of the adult zebrafish electrocardiogram

E Arel, L Rolland, J Thireau, AG Torrente, E Bechard… - bioRxiv, 2022 - biorxiv.org
Background The use of zebrafish to explore cardiac physiology has been widely adopted
within the scientific community. Whether this animal model can be used to determine drug …