The Lyon Consensus provides conclusive criteria for and against the diagnosis of gastro-
oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD …

Background & Aims As many as one-half of all patients with suspected gastroesophageal
reflux disease (GERD) do not derive benefit from acid suppression. This review outlines a …

Laryngopharyngeal reflux (LPR) is a syndrome caused by reflux of gastric contents into the
pharynx or larynx, which leads to symptoms of throat clearing, hoarseness, pain, globus …

Key Clinical Points Gastroesophageal Reflux Disease Patients with heartburn and
symptoms such as dysphagia, odynophagia, weight loss, anorexia, gastrointestinal …

Gastroesophageal reflux disease (GERD) is one of the most frequent gastrointestinal
disorders. Proton pump inhibitors (PPIs) are effective in healing lesions and improving …

Background and Aims Acid exposure time (AET) and reflux episode thresholds from the
Lyon Consensus may not apply for pH impedance studies performed while on proton pump …

Background A hierarchical approach for gastro‐oesophageal reflux disease (GERD)
diagnosis by impedance‐pH monitoring was proposed by the Lyon Consensus, based on …

Gastroesophageal reflux disease has an increasing incidence and prevalence worldwide. A
significant proportion of patients have a suboptimal response to proton pump inhibitors or …

ABSTRACT Introduction Proton pump inhibitors (PPIs) have revolutionized the management
of acid-related disorders, representing today the mainstay treatment of these conditions …

Background and Aims Heartburn is the most common symptom seen in gastroenterology
practice. We aimed to optimize cost-effective evaluation and management of heartburn …