Schizophrenia—an overview
RA McCutcheon, TR Marques, OD Howes - JAMA psychiatry, 2020 - jamanetwork.com
Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical …
encounter regularly during their practice. This report provides an overview of the clinical …
The Hierarchical Taxonomy of Psychopathology (HiTOP): A dimensional alternative to traditional nosologies.
The reliability and validity of traditional taxonomies are limited by arbitrary boundaries
between psychopathology and normality, often unclear boundaries between disorders …
between psychopathology and normality, often unclear boundaries between disorders …
Dopamine and glutamate in schizophrenia: biology, symptoms and treatment
RA McCutcheon, JH Krystal, OD Howes - World Psychiatry, 2020 - Wiley Online Library
Glutamate and dopamine systems play distinct roles in terms of neuronal signalling, yet both
have been proposed to contribute significantly to the pathophysiology of schizophrenia. In …
have been proposed to contribute significantly to the pathophysiology of schizophrenia. In …
Economics and mental health: the current scenario
Economics and mental health are intertwined. Apart from the accumulating evidence of the
huge economic impacts of mental ill‐health, and the growing recognition of the effects that …
huge economic impacts of mental ill‐health, and the growing recognition of the effects that …
Schizophrenia is a cognitive illness: time for a change in focus
Schizophrenia is currently classified as a psychotic disorder. This article posits that this
emphasis on psychosis is a conceptual fallacy that has greatly contributed to the lack of …
emphasis on psychosis is a conceptual fallacy that has greatly contributed to the lack of …
Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations
A McCleery, KH Nuechterlein - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
Despite effective pharmacological treatments for psychotic symptoms (eg, hallucinations,
delusions), functional outcomes for people with psychotic disorders are often disappointing …
delusions), functional outcomes for people with psychotic disorders are often disappointing …
Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders associated with
cognitive impairment, which is considered a major determinant of functional outcome …
cognitive impairment, which is considered a major determinant of functional outcome …
[HTML][HTML] Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia
DA Lewis, AA Curley, JR Glausier, DW Volk - Trends in neurosciences, 2012 - cell.com
Deficits in cognitive control, a core disturbance of schizophrenia, appear to emerge from
impaired prefrontal gamma oscillations. Cortical gamma oscillations require strong inhibitory …
impaired prefrontal gamma oscillations. Cortical gamma oscillations require strong inhibitory …
How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association
Objective: The presence of anxiety disorders (AD) in schizophrenia (SZ) is attracting
increasing interest. However, published studies have yielded very broad variations in …
increasing interest. However, published studies have yielded very broad variations in …
A systematic review of factors influencing adherence to antipsychotic medication in schizophrenia-spectrum disorders
Adherence to antipsychotics improves outcome in schizophrenia. There is a lack of
consensus on which factors most influence adherence behaviour and methodological …
consensus on which factors most influence adherence behaviour and methodological …