Fucoidans are sulfated polysaccharides from brown seaweeds with a variety of biological
properties, which are dependent on both their composition and structure, and are …

Introduction: Off-target effects represent one of the major concerns in the development of
new pharmaceuticals, requiring large-scale animal toxicity testing. Faster, cheaper and more …

Loss of mechanosensory hair cells in the inner ear leads to loss of hearing. In humans this
results in permanent deafness, as mammals are largely unable to regenerate hair cells. In …

Exposure to continuous moderate noise levels is known to impair the auditory system
leading to Noise-Induced Hearing Loss (NIHL) in animals including humans. The …

Sensory hair cells are specialized mechanotransductive receptors required for hearing and
vestibular function. Loss of hair cells in humans and other mammals is permanent and …

Marine plants, animals and microorganisms display steady growth in the ocean and are
abundant carbohydrate resources. Specifically, natural polysaccharides obtained from …

Zebrafish are increasingly used in auditory studies, in part due to the development of several
transgenic lines that express hair cell-specific fluorescent proteins. However, it is largely …

Environmental pollution poses risks to ecosystems. Among these risks, one finds
neurotoxicity and damage to the lateral line structures of fish, such as the neuromast and its …

The majority of hearing loss is caused by the permanent loss of inner ear hair cells. The
identification of drugs that modulate the susceptibility to hair cell loss or spur their …

Hair cell-driven mechanosensory systems are crucial for successful execution of a number
of behaviors in fishes, and have emerged as good models for exploring questions relevant …