Suicide is a major cause of death among patients with schizophrenia. Research indicates
that at least 5–13% of schizophrenic patients die by suicide, and it is likely that the higher …

These updated guidelines are based on the first edition of the World Federation of Societies
of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia …

Antidepressant drugs have often been used as an augmentation strategy for those patients
who have demonstrated a suboptimal response to clozapine. The present 16-week double …

This study assessed changes in depressive symptoms over time in 57 patients with first-
episode psychosis, and investigated the relationships of these symptoms during the acute …

Venlafaxine and the atypical antipsychotic quetiapine are often administered concomitantly.
Both drugs share several metabolic hepatic pathways. However, pharmacokinetic …

Background Depressive episodes in schizophrenia constitute a major clinical problem, and
treatment success is often limited by treatment-emergent side effects. Agomelatine, an …

Introduction: Although the pathogenesis of symptoms of schizophrenia is largely unknown, a
variety of neurotransmitters are implicated, including serotonin and norepinephrine. Here we …

Patients with psychotic disorders often suffer from intercurrent major depressive episodes
(MDE). Case reports suggested successful antidepressive treatment with duloxetine, a …

Purpose This study aimed to investigate the influence of diagnosis, body weight, sex, age,
smoking, formulations, and concomitant drugs on steady‐state dose‐corrected serum …

Аннотация Депрессия является одним из наиболее распространенных сопутствующих
синдромов при шизофрении, ассоциированным с ухудшением качества жизни …