The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

Developing a mechanistic understanding of the impact of food structure and composition on
human health has increasingly involved simulating digestion in the upper gastrointestinal …

Amyloid fibrils have traditionally been considered only as pathological aggregates in human
neurodegenerative diseases, but it is increasingly becoming clear that the propensity to form …

The link between food and human health is increasingly a topic of interest. One avenue of
study has been to assess food disintegration and interactions within the gastrointestinal …

Mucus is a selective barrier to particles and molecules, preventing penetration to the
epithelial surface of mucosal tissues. Significant advances in transmucosal drug delivery …

Simulated gastro-intestinal digestion is widely employed in many fields of food and
nutritional sciences, as conducting human trials are often costly, resource intensive, and …

Colon-specific drug delivery systems (CDDS) are desirable for the treatment of a range of
local diseases such as ulcerative colitis, Crohn's disease, irritable bowel syndrome, chronic …

Oral administration is the most common route of drug delivery. The absorption of a drug from
the gut into the bloodstream involves disintegration of the solid dosage form, dissolution of …

The ubiquitous soil bacterium Bacillus cereus presents major challenges to food safety. It is
responsible for two types of food poisoning, the emetic form due to food intoxication and the …