[HTML][HTML] Role of fibrinolytic enzymes in anti-thrombosis therapy

F Altaf, S Wu, V Kasim - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Thrombosis, a major cause of deaths in this modern era responsible for 31% of all global
deaths reported by WHO in 2017, is due to the aggregation of fibrin in blood vessels which …

[HTML][HTML] Microbial fibrinolytic enzymes as anti-thrombotics: production, characterisation and prodigious biopharmaceutical applications

C Sharma, A Osmolovskiy, R Singh - Pharmaceutics, 2021 - mdpi.com
Cardiac disorders such as acute myocardial infarction, embolism and stroke are primarily
attributed to excessive fibrin accumulation in the blood vessels, usually consequential in …

[HTML][HTML] Thrombolytic enzymes of microbial origin: a review

D Diwan, Z Usmani, M Sharma, JW Nelson… - International journal of …, 2021 - mdpi.com
Enzyme therapies are attracting significant attention as thrombolytic drugs during the current
scenario owing to their great affinity, specificity, catalytic activity, and stability. Among various …

Anti‐MRSA and clot lysis activities of Pestalotiopsis microspora isolated from Dillenia pentagyna Roxb

S Chowdhury, S Ghosh, SK Gond - Journal of Basic …, 2023 - Wiley Online Library
There is an urgent call to search for novel natural compounds against developing multidrug‐
resistant microorganisms. The present work focuses on the characterization of a plant …

Thrombolytic and anticoagulant efficiencies of purified fibrinolytic enzyme produced from Cochliobolus hawaiiensis under solid‐state fermentation

MA Abu‐Tahon, AM Abdel‐Majeed… - Biotechnology and …, 2023 - Wiley Online Library
Abstract Cochliobolus hawaiiensis Alcorn Assiut University Mycological Centre 8606 was
chosen from the screened 20 fungal species as the potent producer of fibrinolytic enzyme on …

Characteristics and Properties of the Complex of Proteolytic Enzymes of the Thrombolytic Action of the Micromycete Sarocladium strictum

EI Kornienko, AA Osmolovskiy, VG Kreyer… - Applied Biochemistry …, 2021 - Springer
A preparation of thrombolytic enzymes of micromycete S. strictum 203 was obtained and
characterized. The expressed urokinase activity of producer proteinases was determined …

Production of proteinases with fibrinolytic and fibrinogenolytic activity by a micromycete Aspergillus ochraceus

AA Osmolovskiy, ED Rukavitsyna, VG Kreier… - Microbiology, 2017 - Springer
Fibrinolytic and fibrinogenolytic activity of surface and submerged cultures of a micromycete
Aspergillus ochraceus L-1 was studied. Extracellular proteinases produced by A. ochraceus …

[HTML][HTML] Action of Extracellular Proteases of Aspergillus flavus and Aspergillus ochraceus Micromycetes on Plasma Hemostasis Proteins

AA Osmolovskiy, L Schmidt, AV Orekhova… - Life, 2021 - mdpi.com
In this study, we investigated the properties of proteolytic enzymes of two species of
Aspergillus, Aspergillus flavus 1 (with a high degree of pathogenicity) and Aspergillus …

Properties of extracellular plasmin-like proteases of Aspergillus ochraceus micromycete

AA Osmolovskiy, VG Kreier, NA Baranova… - Applied Biochemistry …, 2017 - Springer
The properties of two extracellular proteases of Aspergillus ochraceus VKM F-4104D
micromycete with plasmin-like activity have been studied. It has been shown that the …

Ability of extracellular proteinases of micromycetes Aspergillus flavipes, Aspergillus fumigatus, and Aspergillus sydowii to affect proteins of the human haemostatic …

AA Osmolovskiy, AV Kurakov, VG Kreyer… - Moscow University …, 2017 - Springer
The effect of extracellular proteinases of A. flavipes A17, A. fumigatus D1, and A. sydowii 1
on proteins of the human haemostasis system was studied. It was shown that A. fumigatus …