A number of pharmacologic treatments examined in recent randomized clinical trials (RCTs)
have failed to show statistically significant superiority to placebo in conditions in which their …

Although neuropathic pain can be acute in nature, in most patients the pain is persistent (or
“refractory”). Patients with chronic neuropathic pain are seen most often in clinical practice. It …

Background Tibia shaft fractures (TSF) are common for men and women and cause
substantial morbidity, healthcare use, and costs. The impact of nonunions on healthcare use …

Background The efficacy of exercise-based telerehabilitation in chronic low back pain
(CLBP) has not been well studied. To our knowledge, no other studies have investigated the …

Background Poor sleep is a frequent symptom in patients with multiple sclerosis (MS). Sleep
may be influenced by MS-related symptoms and adverse effects from immunotherapy and …

The aim of this study was to compare pain and its relationship with the oral quality of life of
patients with different types of orthodontic appliances: conventional and conventional low …

Individual differences in emotional functioning, pain appraisal processing, and perceived
social support may play a relevant role in the subjective experience of pain. Due to the …

Bone fractures commonly repair by forming a bridging structure called callus, which begins
as soft tissue and gradually ossifies to restore rigidity to the bone. Virtual mechanical testing …

Despite the availability of effective pain treatments, there are numerous barriers to effective
management resulting in a large proportion of patients not achieving optimal pain control …

Inflammatory bowel disease (IBD) is frequently associated with chronic abdominal pain
(CAP). Transcranial direct current stimulation (tDCS) has been proven to reduce chronic …