The progression from gestation into lactation represents the transition period, and it is
accompanied by marked physiological, metabolic, and inflammatory adjustments. The entire …

The growing field of immunometabolism has taught us how metabolic cellular reactions and
processes not only provide a means to generate ATP and biosynthetic precursors, but are …

The Warburg effect, which originally described increased production of lactate in cancer, is
associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of …

The kynurenine pathway (KP) plays a critical role in generating cellular energy in the form of
nicotinamide adenine dinucleotide (NAD+). Because energy requirements are substantially …

Circulating concentrations of the pleiotropic cytokine interleukin-6 (IL-6) are known to be
increased in pro-inflammatory critical care syndromes, such as sepsis and acute respiratory …

Diabetes mellitus type II and obesity are two important causes of death in modern society.
They are characterized by low-grade chronic inflammation and metabolic dysfunction (meta …

The pandemic of coronavirus disease 2019 (COVID-19) and its pathogen, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) have become the greatest current threat …

Inflammatory Arthritis is characterized by synovial proliferation, neovascularization and
leukocyte extravasation leading to joint destruction and functional disability. Efficiency of …

Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

Sepsis occurs when an infection exceeds local tissue containment and induces a series of
dysregulated physiologic responses that result in organ dysfunction. A subset of patients …