[HTML][HTML] Natural cyclopeptides as anticancer agents in the last 20 years

JN Zhang, YX Xia, HJ Zhang - International Journal of Molecular Sciences, 2021 - mdpi.com
Cyclopeptides or cyclic peptides are polypeptides formed by ring closing of terminal amino
acids. A large number of natural cyclopeptides have been reported to be highly effective …

[HTML][HTML] Culture-dependent bioprospecting of bacterial isolates from the Canadian high Arctic displaying antibacterial activity

E Marcolefas, T Leung, M Okshevsky… - Frontiers in …, 2019 - frontiersin.org
The goal of this study was to isolate, screen, and characterize Arctic microbial isolates from
Expedition Fjord, Axel Heiberg Island, Nunavut, Canada capable of inhibiting the growth of …

[HTML][HTML] Identification by Genome Mining of a Type I Polyketide Gene Cluster from Streptomyces argillaceus Involved in the Biosynthesis of Pyridine and Piperidine …

S Ye, B Molloy, AF Braña, D Zabala, C Olano… - Frontiers in …, 2017 - frontiersin.org
Genome mining of the mithramycin producer Streptomyces argillaceus ATCC 12956
revealed 31 gene clusters for the biosynthesis of secondary metabolites, and allowed to …

[HTML][HTML] Sampling terrestrial environments for bacterial polyketides

P Hill, GW Heberlig, CN Boddy - Molecules, 2017 - mdpi.com
Bacterial polyketides are highly biologically active molecules that are frequently used as
drugs, particularly as antibiotics and anticancer agents, thus the discovery of new …

Endophytic microbes as a novel source for producing anticancer compounds as multidrug resistance modulators

JAC Filho - … Products and Biotechnological Implements: Volume 2, 2018 - Springer
Endophytes are a range of microorganisms which inhabit the plant tissues, establishing an
association with their hosts during a period for nearly or all their life without causing any …

Production and application of novel bio-active compounds by endophytic microbes

JAC Filho - Natural Bio-active Compounds: Volume 1: Production …, 2019 - Springer
Traditionally, endophytes are microorganisms that inhabit plant tissues, establishing an
association with their hosts for most or all of their life without causing any apparent damage …

[图书][B] Expansion, Synthesis, and Biological Evaluation of a Focused Library of N-Substituted Indolines and 1, 2, 3, 4-Tetrahyrdoquinolines as Antimicrobials

H Lupton - 2020 - search.proquest.com
Infectious diseases and their resistance to common antibiotics are a growing source of
concern, affecting hundreds of millions of people across the globe. New classes of …

Liquid Chromatography for Plant Metabolite Profiling in the Field of Drug Discovery

LC Klein-Júnior, J Viaene, A Slosse… - Natural Products as …, 2018 - Springer
Although medicine has undergone massive evolutions, challenges are still present.
Technological evolutions have had a major influence on the drug discovery process. As a …