Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections.
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …

Increasing evidence supports a central role of the immune system in sepsis, but the current
view of how sepsis affects immunity, and vice versa, is still rudimentary. The European …

Background The novel coronavirus disease 2019 (COVID-19) has become a global health
emergency. The cumulative number of new confirmed cases and deaths are still increasing …

Burn injury induces a complex inflammatory response, both locally and systemically, and is
not yet completely unravelled and understood. In order to enable the development of …

Rationale: Although early antimicrobial discontinuation guided by procalcitonin (PCT) has
shown decreased antibiotic consumption in lower respiratory tract infections, the outcomes …

A biomarker is a molecule that can be measured in a biological sample in an objective,
systematic, and precise way, whose levels indicate whether a process is normal or …

Abstract Background Procalcitonin (PCT) and C-reactive protein (CRP) were previously
shown to have value for the detection of secondary infections in critically ill COVID-19 …

Since December 2019, a novel coronavirus (severe acute respiratory syndrome—
coronavirus 2, SARS-CoV-2) has rapidly spread around the world resulting in an acute …

Important aspects of sepsis management include early diagnosis as well as timely and
specific treatment in the first few hours of triage. However, diagnosis and differentiation from …

Procalcitonin as an antibiotic stewardship tool in COVID-19 patients in the intensive care unit -
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