Erythropoietin and derivatives: Potential beneficial effects on the brain

DC Vittori, ME Chamorro, YV Hernández… - Journal of …, 2021 - Wiley Online Library
Erythropoietin (Epo), the main erythropoiesis‐stimulating factor widely prescribed to
overcome anemia, is also known nowadays for its cytoprotective action on non …

[HTML][HTML] The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments

RM Kaminski, MA Rogawski, H Klitgaard - Neurotherapeutics, 2014 - Elsevier
A major goal of contemporary epilepsy research is the identification of therapies to prevent
the development of recurrent seizures in individuals at risk, including those with brain …

[HTML][HTML] Insights into potential targets for therapeutic intervention in epilepsy

C Zavala-Tecuapetla, M Cuellar-Herrera… - International journal of …, 2020 - mdpi.com
Epilepsy is a chronic brain disease that affects approximately 65 million people worldwide.
However, despite the continuous development of antiepileptic drugs, over 30% patients with …

[HTML][HTML] Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive …

C Corley, T McElroy, B Sridharan, M Trujillo… - Frontiers in …, 2023 - frontiersin.org
Introduction Chemotherapy-induced cognitive impairment colloquially referred to as
chemobrain is a poorly understood phenomenon affecting a highly variable proportion of …

EPO and EPO-receptor system as potential actionable mechanism for the protection of brain and heart in refractory epilepsy and SUDEP

J Auzmendi, MB Puchulu… - Current …, 2020 - ingentaconnect.com
The most important activity of erythropoietin (EPO) is the regulation of erythrocyte production
by activation of the erythropoietin receptor (EPO-R), which triggers the activation of anti …

[PDF][PDF] Use of Cuban recombinant human erythropoietin in Parkinson's disease treatment

I Pedroso, ML Bringas, A Aguiar, L Morales… - MEDICC …, 2012 - SciELO Public Health
INTRODUCTION Recombinant human erythropoietin is used primarily to treat anemia.
There is evidence of its neuroprotective capacity from preclinical studies in Parkinson's …

Targeting erythropoietin for chronic neurodegenerative diseases

ZZ Chong, YC Shang, Y Mu, S Cui, Q Yao… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Since erythropoietin (EPO) and EPO receptor (EPOR) are expressed in the
central nervous system (CNS) beyond hematopoietic system, EPO illustrates a robust …

Short erythropoietin-derived peptide enhances memory, improves long-term potentiation, and counteracts amyloid beta–induced pathology

O Dmytriyeva, A Belmeguenai, L Bezin, K Soud… - Neurobiology of …, 2019 - Elsevier
Neurodegenerative disorders such as Alzheimer's disease (AD) are characterized by the
irreversible neuronal loss and memory impairment, and current treatments are merely …

Erythropoietin pretreatment suppresses seizures and prevents the increase in inflammatory mediators during pentylenetetrazole-induced generalized seizures

N Bahçekapılı, K Akgün-Dar, I Albeniz… - International Journal …, 2014 - Taylor & Francis
Erythropoietin (EPO) suppresses epileptic seizures, but the mechanism is unclear. The
search for novel targets in the therapy of epilepsy has focused recently on brain …

[HTML][HTML] Incidence rate and risk factors of status epilepticus after stroke

H Wang, D Chen, G Tan, LN Zhu, L Liu - Seizure, 2021 - Elsevier
Purpose To evaluate the incidence rate and risk factors for status epilepticus (SE) after
stroke (PSSE), including ischaemic stroke (IS), intracerebral hemorrhage (ICH), and …