Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

Being versus appearing socially uninterested: Challenging assumptions about social motivation in autism

VK Jaswal, N Akhtar - Behavioral and Brain Sciences, 2019 - cambridge.org
Progress in psychological science can be limited by a number of factors, not least of which
are the starting assumptions of scientists themselves. We believe that some influential …

An amygdala-to-hypothalamus circuit for social reward

RK Hu, Y Zuo, T Ly, J Wang, P Meera, YE Wu… - Nature …, 2021 - nature.com
Social interactions and relationships are often rewarding, but the neural mechanisms
through which social interaction drives positive experience remain poorly understood. In this …

Evaluation of the social motivation hypothesis of autism: a systematic review and meta-analysis

CC Clements, AR Zoltowski, LD Yankowitz… - JAMA …, 2018 - jamanetwork.com
Importance The social motivation hypothesis posits that individuals with autism spectrum
disorder (ASD) find social stimuli less rewarding than do people with neurotypical activity …

Prefrontal cortex and social cognition in mouse and man

LK Bicks, H Koike, S Akbarian, H Morishita - Frontiers in psychology, 2015 - frontiersin.org
Social cognition is a complex process that requires the integration of a wide variety of
behaviors, including salience, reward-seeking, motivation, knowledge of self and others …

The social motivation theory of autism

C Chevallier, G Kohls, V Troiani, ES Brodkin… - Trends in cognitive …, 2012 - cell.com
The idea that social motivation deficits play a central role in Autism Spectrum Disorders
(ASD) has recently gained increased interest. This constitutes a shift in autism research …

A dopamine hypothesis of autism spectrum disorder

D Pavăl - Developmental neuroscience, 2017 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. While several theories have …

Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors

PE Rothwell, MV Fuccillo, S Maxeiner, SJ Hayton… - Cell, 2014 - cell.com
In humans, neuroligin-3 mutations are associated with autism, whereas in mice, the
corresponding mutations produce robust synaptic and behavioral changes. However …

[图书][B] The developing mind: How relationships and the brain interact to shape who we are

DJ Siegel - 2020 - books.google.com
This highly influential work--now in a revised and expanded third edition incorporating major
advances in the field--gives clinicians, educators, and students a new understanding of what …