Human organs-on-chips for disease modelling, drug development and personalized medicine

DE Ingber - Nature Reviews Genetics, 2022 - nature.com
The failure of animal models to predict therapeutic responses in humans is a major problem
that also brings into question their use for basic research. Organ-on-a-chip (organ chip) …

Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery

N Sunildutt, P Parihar… - Frontiers in …, 2023 - frontiersin.org
The inefficiency of existing animal models to precisely predict human pharmacological
effects is the root reason for drug development failure. Microphysiological system/organ-on …

State of the Art in 3D Culture Models Applied to Thyroid Cancer

A Prete, A Matrone, R Plebani - Medicina, 2024 - mdpi.com
Thyroid cancer (TC) is the prevalent endocrine tumor with a rising incidence, particularly in
higher-income countries, leading to an increased interest in its management and treatment …