Inflammation and fibrosis
M Mack - Matrix Biology, 2018 - Elsevier
Tissue damage and inflammation are important triggers for regeneration and fibrosis. Tissue
damage not only induces inflammation in general, it also determines the type and …
damage not only induces inflammation in general, it also determines the type and …
Role of galectin 3 binding protein in cancer progression: a potential novel therapeutic target
E Capone, S Iacobelli, G Sala - Journal of translational medicine, 2021 - Springer
The lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a secreted,
hyperglycosylated protein expressed by the majority of human cells. It was first identified as …
hyperglycosylated protein expressed by the majority of human cells. It was first identified as …
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
The heterogeneity of exosomal populations has hindered our understanding of their
biogenesis, molecular composition, biodistribution and functions. By employing asymmetric …
biogenesis, molecular composition, biodistribution and functions. By employing asymmetric …
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
Interferon-stimulated genes (ISGs) form the backbone of the innate immune system and are
important for limiting intra-and intercellular viral replication and spread. We conducted a …
important for limiting intra-and intercellular viral replication and spread. We conducted a …
Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis
S Takeuchi, A Tsuchiya, T Iwasawa, S Nojiri… - NPJ Regenerative …, 2021 - nature.com
Mesenchymal stromal cells (MSCs) are used for ameliorating liver fibrosis and aiding liver
regeneration after cirrhosis; Here, we analyzed the therapeutic potential of small …
regeneration after cirrhosis; Here, we analyzed the therapeutic potential of small …
Development of galectin-3 targeting drugs for therapeutic applications in various diseases
R Ahmed, K Anam, H Ahmed - International Journal of Molecular …, 2023 - mdpi.com
Galectin-3 (Gal3) is one of the most studied members of the galectin family that mediate
various biological processes such as growth regulation, immune function, cancer …
various biological processes such as growth regulation, immune function, cancer …
The development of serum amyloid P as a possible therapeutic
Pentraxins such as serum amyloid P (SAP; also known as PTX2) regulate several aspects of
the innate immune system. SAP inhibits the differentiation of monocyte-derived fibroblast …
the innate immune system. SAP inhibits the differentiation of monocyte-derived fibroblast …
Galectin-3-binding protein: A multitask glycoprotein with innate immunity functions in viral and bacterial infections
V Loimaranta, J Hepojoki, O Laaksoaho… - Journal of leukocyte …, 2018 - academic.oup.com
Abstract Galectin-3-binding protein (Gal-3BP) is a ubiquitous and multifunctional secreted
glycoprotein originally identified and mainly studied in the context of neoplastic …
glycoprotein originally identified and mainly studied in the context of neoplastic …
Using tears as a non-invasive source for early detection of breast cancer
A Daily, P Ravishankar, S Harms, VS Klimberg - PLoS One, 2022 - journals.plos.org
The changing expression levels of ocular proteins in response to systemic disease has been
well established in literature. In this study, we examined the ocular proteome to identify …
well established in literature. In this study, we examined the ocular proteome to identify …
Surfaceome proteomic of glioblastoma revealed potential targets for immunotherapy
Glioblastoma (GBM) is the most common and devastating malignant brain tumor in adults.
The mortality rate is very high despite different treatments. New therapeutic targets are …
The mortality rate is very high despite different treatments. New therapeutic targets are …