Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment

J Burgess, M Ferdousi, D Gosal, C Boon… - Oncology and …, 2021 - Springer
Purpose This review provides an update on the current clinical, epidemiological and
pathophysiological evidence alongside the diagnostic, prevention and treatment approach …

Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Pathophysiology of chemotherapy-induced peripheral neuropathy

H Starobova, I Vetter - Frontiers in molecular neuroscience, 2017 - frontiersin.org
Chemotherapy-induced neuropathy is a common, dose-dependent adverse effect of several
antineoplastics. It can lead to detrimental dose reductions and discontinuation of treatment …

[HTML][HTML] Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis

M Seretny, GL Currie, ES Sena, S Ramnarine, R Grant… - Pain®, 2014 - Elsevier
Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling pain condition resulting
from chemotherapy for cancer. Severe acute CIPN may require chemotherapy dose …

Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice …

DL Hershman, C Lacchetti, RH Dworkin… - Journal of clinical …, 2014 - ascopubs.org
Purpose To provide evidence-based guidance on the optimum prevention and treatment
approaches in the management of chemotherapy-induced peripheral neuropathies (CIPN) …

[HTML][HTML] Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity–Exploring the armoury of obscurity

K Singh, M Bhori, YA Kasu, G Bhat, T Marar - Saudi Pharmaceutical Journal, 2018 - Elsevier
Cancer is the leading cause of mortality worldwide, accounting for almost 13% of deaths in
the world. Among the conventional cancer treatments, chemotherapy is most frequently …

Chemotherapy‐induced peripheral neurotoxicity: a critical analysis

SB Park, D Goldstein, AV Krishnan… - CA: a cancer journal …, 2013 - Wiley Online Library
With a 3‐fold increase in the number of cancer survivors noted since the 1970s, there are
now over 28 million cancer survivors worldwide. Accordingly, there is a heightened …

The Odyssey of Bioactive Compounds in Avocado (Persea americana) and Their Health Benefits

DJ Bhuyan, MA Alsherbiny, S Perera, M Low, A Basu… - Antioxidants, 2019 - mdpi.com
Persea americana, commonly known as avocado, has recently gained substantial popularity
and is often marketed as a “superfood” because of its unique nutritional composition …

[HTML][HTML] Oxidative stress and nerve damage: role in chemotherapy induced peripheral neuropathy

A Areti, VG Yerra, VGM Naidu, A Kumar - Redox biology, 2014 - Elsevier
Peripheral neuropathy is a severe dose limiting toxicity associated with cancer
chemotherapy. Ever since it was identified, the clear pathological mechanisms underlying …

Chemotherapy-induced peripheral neurotoxicity (CIPN): an update

AA Argyriou, J Bruna, P Marmiroli, G Cavaletti - Critical reviews in oncology …, 2012 - Elsevier
The peripheral nervous system can be vulnerable to the toxic action of several drugs since it
is not protected as effectively as the central nervous system from noxious exogenous agents …