Neural circuits and the cells that comprise them represent the functional units of the brain.
Circuits relay and process sensory information, maintain homeostasis, drive behaviors, and …

Highlights•The new, faster generation of GEVIs facilitate more precise neuronal activity
recordings.•GEVI optimization is a 'work in progress'.•GEVIs adoption for use in various …

Imaging voltage using fluorescent-based sensors could be an ideal technique to probe
neural circuits with high spatiotemporal resolution. However, due to insufficient signal-to …

The thalamus controls transmission of sensory signals from periphery to cortex, ultimately
shaping perception. Despite this significant role, dynamic thalamic gating and the …

Sensory inputs carry critical information for the survival of an organism. In mice, tactile
information conveyed by the whiskers is of high behavioural relevance, and is broadcasted …

Sensors for imaging brain activity have been under development for almost 50 years. The
development of some of these tools is relatively mature, whereas qualitative improvements …

Objective. Controlling neural activity enables the possibility of manipulating sensory
perception, cognitive processes, and body movement, in addition to providing a powerful …

Neurological disorders display a broad spectrum of clinical manifestations. Yet, at the
cellular level, virtually all these diseases converge into a common phenotype of …

Genetically encoded voltage indicators (GEVIs) allow optical recordings of membrane
potential changes in defined cell populations. Transgenic reporter animals that facilitate …

Cholinergic modulation of brain activity is fundamental for awareness and conscious
sensorimotor behaviours, but deciphering the timing and significance of acetylcholine …