The “Janus Face” of platelets in cancer

MV Catani, I Savini, V Tullio, V Gasperi - International journal of molecular …, 2020 - mdpi.com
Besides their vital role in hemostasis and thrombosis, platelets are also recognized to be
involved in cancer, where they play an unexpected central role: They actively influence …

Bidirectional interaction between cancer cells and platelets provides potential strategies for cancer therapies

L Yu, Y Guo, Z Chang, D Zhang, S Zhang, H Pei… - Frontiers in …, 2021 - frontiersin.org
Platelets are essential components in the tumor microenvironment. For decades, clinical
data have demonstrated that cancer patients have a high risk of thrombosis that is …

Evaluating the prognostic significance of preoperative thrombocytosis in epithelial ovarian cancer

SK Allensworth, CL Langstraat, JR Martin… - Gynecologic …, 2013 - Elsevier
Objective Preoperative thrombocytosis has been implicated as a negative prognostic marker
for epithelial ovarian cancer (EOC). We assessed whether thrombocytosis is an independent …

Preoperative thrombocytosis is associated with survival after surgery for colorectal cancer

M Ishizuka, H Nagata, K Takagi… - Journal of surgical …, 2012 - Wiley Online Library
Objective To evaluate the influence of preoperative thrombocytosis on survival after surgery
in patients with colorectal cancer (CRC). Methods Four hundred fifty‐three patients who had …

[HTML][HTML] Thrombocytosis as a prognostic marker in gastrointestinal cancers

IA Voutsadakis - World journal of gastrointestinal oncology, 2014 - ncbi.nlm.nih.gov
Thrombocytosis is an adverse prognostic factor in many types of cancer. These include
breast cancer, ovarian and other gynecologic cancers, renal cell carcinoma and lung …

Paraneoplastic thrombocytosis independently predicts poor prognosis in patients with locally advanced pancreatic cancer

AS Chadha, E Kocak-Uzel, P Das, BD Minsky… - Acta …, 2015 - Taylor & Francis
Background and aims. Platelets are believed to promote tumor growth and metastasis but
their prognostic role in locally advanced pancreatic cancer (LAPC) remains largely …

Colorectal cancer and hypercoagulability

K Kawai, T Watanabe - Surgery today, 2014 - Springer
Since the first report of the spontaneous appearance of venous thrombophlebitis as a sign of
visceral cancer by Trousseau in 1865, many other studies have documented the existence …

Paraneoplastic thrombocytosis in gastrointestinal cancer

Z Baranyai, V Jósa, A Tóth, Z Szilasi, B Tihanyi… - Platelets, 2016 - Taylor & Francis
It has been demonstrated recently in several solid tumors that thrombocytosis at diagnosis
may correlate with tumor invasion, metastatic progression and worse outcome. Several …

Platelet and epithelial cell interations can be modeled in cell culture, and are not affected by dihomo-gamma-linolenic acid

ZR Isingizwe, LF Mortan, DM Benbrook - Plos one, 2024 - journals.plos.org
Increasing evidence is implicating roles for platelets in the development and progression of
ovarian cancer, a highly lethal disease that can arise from the fallopian tubes, and has no …

[HTML][HTML] Thrombocytosis is a significant indictor of hypercoagulability, prognosis and recurrence in gastric cancer

C Hu, R Chen, W Chen, W Pang… - Experimental and …, 2014 - spandidos-publications.com
Although thrombocytosis has been reported in a variety of cancer types, the standard of
thrombocytosis in gastric cancer (GC) and the association between thrombocytosis and the …