[HTML][HTML] Regulation of cancer stem cells in triple negative breast cancer
N Fultang, M Chakraborty… - Cancer Drug …, 2021 - ncbi.nlm.nih.gov
Abstract Triple Negative Breast Cancer (TNBC) is the most lethal subtype of breast cancer.
Despite the successes of emerging targeted therapies, relapse, recurrence, and therapy …
Despite the successes of emerging targeted therapies, relapse, recurrence, and therapy …
Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures
J Dornhof, J Kieninger, H Muralidharan, J Maurer… - Lab on a Chip, 2022 - pubs.rsc.org
Three-dimensional cell cultures using patient-derived stem cells are essential in vitro
models for a more efficient and individualized cancer therapy. Currently, culture conditions …
models for a more efficient and individualized cancer therapy. Currently, culture conditions …
[HTML][HTML] Trailblazing perspectives on targeting breast cancer stem cells
Breast cancer (BCa) is one of the most prevalent malignant tumors affecting women's health
worldwide. The recurrence and metastasis of BCa have made it a long-standing challenge …
worldwide. The recurrence and metastasis of BCa have made it a long-standing challenge …
Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix
F De Lorenzi, N Hansen, B Theek, R Daware… - Advanced …, 2024 - Wiley Online Library
Advanced in vitro systems such as multicellular spheroids and lab‐on‐a‐chip devices have
been developed, but often fall short in reproducing the tissue scale and self‐organization of …
been developed, but often fall short in reproducing the tissue scale and self‐organization of …
HSPB1 facilitates chemoresistance through inhibiting ferroptotic cancer cell death and regulating NF-κB signaling pathway in breast cancer
Y Liang, Y Wang, Y Zhang, F Ye, D Luo, Y Li… - Cell Death & …, 2023 - nature.com
Chemoresistance is one of the major causes of therapeutic failure and poor prognosis for
breast cancer patients, especially for triple-negative breast cancer patients. However, the …
breast cancer patients, especially for triple-negative breast cancer patients. However, the …
A computational systems biology approach identifies SLUG as a mediator of partial Epithelial-Mesenchymal Transition (EMT)
Epithelial-mesenchymal plasticity comprises reversible transitions among epithelial, hybrid
epithelial/mesenchymal (E/M) and mesenchymal phenotypes, and underlies various aspects …
epithelial/mesenchymal (E/M) and mesenchymal phenotypes, and underlies various aspects …
Tumor Necrosis Factor-α (TNFα) Stimulates Triple-Negative Breast Cancer Stem Cells to Promote Intratumoral Invasion and Neovasculogenesis in the Liver of a …
H Narasimhan, F Ferraro, A Bleilevens, R Weiskirchen… - Biology, 2022 - mdpi.com
Simple Summary In this study, we investigated the effect of TNFα on primary triple-negative
breast cancer (TNBC) stem cells to understand the role of TNFα in vascular attraction in the …
breast cancer (TNBC) stem cells to understand the role of TNFα in vascular attraction in the …
Plecstatin-1 induces an immunogenic cell death signature in colorectal tumour spheroids
D Wernitznig, SM Meier-Menches, K Cseh… - Metallomics, 2020 - academic.oup.com
Organometallic metal (arene) anticancer agents were believed to confer low selectivity for
potential cellular targets. However, the ruthenium (arene) pyridinecarbothioamide (plecstatin …
potential cellular targets. However, the ruthenium (arene) pyridinecarbothioamide (plecstatin …
HDAC8 suppresses the epithelial phenotype and promotes EMT in chemotherapy-treated basal-like breast cancer
G Pantelaiou-Prokaki, I Mieczkowska, GE Schmidt… - Clinical …, 2022 - Springer
Background Basal-like breast cancer (BLBC) is one of the most aggressive malignant
diseases in women with an increased metastatic behavior and poor prognosis compared to …
diseases in women with an increased metastatic behavior and poor prognosis compared to …
The potential of PSMA as a vascular target in TNBC
A Heesch, L Ortmanns, J Maurer, E Stickeler… - Cells, 2023 - mdpi.com
Recent studies proving prostate-specific membrane antigen (PSMA) expression on triple-
negative breast cancer (TNBC) cells and adjacent endothelial cells suggest PSMA as a …
negative breast cancer (TNBC) cells and adjacent endothelial cells suggest PSMA as a …