Sepsis, a systemic inflammatory response disease, is the most severe complication of
infection and a deadly disease. High mobility group proteins (HMGs) are non-histone …

Wnt/β‐catenin signalling has been suggested to be active in basal‐like breast cancer.
However, in highly aggressive metastatic triple‐negative breast cancers (TNBC) the role of β …

Let-7 is one of the earliest discovered microRNAs (miRNAs) and has been reported to
regulate self renewal and tumorigenicity of breast cancer cells. Let-7a is a member of this …

Purpose: The study of the cancer secretome suggests that a fraction of the intracellular
proteome could play unanticipated roles in the extracellular space during tumorigenesis. A …

High-mobility group AT-hook1 (HMGA1, formerly HMG-I/Y), an architectural transcription
factor, participates in a number of tumor biological processes. However, its effect on cervical …

Sex-determining region Y-related high mobility group box 4 (SOX4) has been proven to
serve as a critical role in cancer development and progression. However, little is known …

Chemoresistance is a poor prognostic factor in breast cancer and is a major obstacle to the
successful treatment of patients receiving chemotherapy. However, the precise mechanism …

Cancer cells acquire genetic and epigenetic alterations that often lead to dysregulation of
oncogenic signal transduction pathways, which in turn alters downstream transcriptional …

Lin28, a highly conserved carcinogenic protein, plays an important role in the generation of
cancer stem cells, contributing to the unfavorable prognosis of cancer patients. This RNA …

As the majority of patients with basal-like breast carcinoma present with invasive, metastatic
disease that do not respond to available therapies, it is essential to identify new therapeutic …