Liver sinusoidal endothelial cells (LSECs) line the low shear, sinusoidal capillary channels
of the liver and are the most abundant non-parenchymal hepatic cell population. LSECs do …

Liver cancer has the fourth highest mortality rate of all cancers worldwide, with
hepatocellular carcinoma (HCC) being the most prevalent subtype. Despite great advances …

In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively
participate in both innate and adaptive immune responses. We previously reported that, in …

Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

LSECs are a unique population of endothelial cells within the liver and are recognized as
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …

This update focuses on two main topics. First, recent developments in our understanding of
liver sinusoidal endothelial cell (LSEC) function will be reviewed, specifically elimination of …

Abstract 'Angiodiversity'refers to the structural and functional heterogeneity of endothelial
cells (EC) along the segments of the vascular tree and especially within the microvascular …

The liver is an important immunological organ that controls systemic tolerance. The liver
harbors professional and unconventional antigen-presenting cells that are crucial for …

Clever-1 (also known as Stabilin-1 and FEEL-1) is a scavenger receptor expressed on
lymphatic endothelial cells, sinusoidal endothelial cells and immunosuppressive monocytes …

The structural and physiological complexity of currently available liver organoids is limited,
thereby reducing their relevance for drug studies, disease modelling, and regenerative …