Emerging materials for hemostasis

XF Li, P Lu, HR Jia, G Li, B Zhu, X Wang… - Coordination Chemistry …, 2023 - Elsevier
Severe hemorrhage has posed a serious threat to the health and even life of civilian and
military populations and brought serious economic losses. Consequently, it is imperative to …

[HTML][HTML] Red blood cells: the forgotten player in hemostasis and thrombosis

JW Weisel, RI Litvinov - Journal of Thrombosis and Haemostasis, 2019 - Elsevier
New evidence has stirred up a long‐standing but undeservedly forgotten interest in the role
of erythrocytes, or red blood cells (RBCs), in blood clotting and its disorders. This review …

Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems

CH Villa, AC Anselmo, S Mitragotri… - Advanced drug delivery …, 2016 - Elsevier
Red blood cells (RBCs) constitute a unique drug delivery system as a biologic or hybrid
carrier capable of greatly enhancing pharmacokinetics, altering pharmacodynamics (for …

Role of red blood cells in haemostasis and thrombosis

RI Litvinov, JW Weisel - ISBT science series, 2017 - Wiley Online Library
In contrast to an obsolete notion that erythrocytes, or red blood cells (RBC s), play a passive
and minor role in haemostasis and thrombosis, over the past decades there has been …

New players in haemostasis and thrombosis

JE Geddings, N Mackman - Thrombosis and haemostasis, 2014 - thieme-connect.com
The blood coagulation cascade is essential for haemostasis, but excessive activation can
cause thrombosis. Importantly, recent studies have identified factors that contribute to …

Red blood cells membrane‐derived nanoparticles: applications and key challenges in their clinical translation

S Malhotra, S Dumoga, N Singh - … Reviews: Nanomedicine and …, 2022 - Wiley Online Library
Cellular membrane‐derived nanoparticles, particularly of red blood cells (RBCs), represent
an emerging class of drug delivery systems. The lack of nucleus and organelles in these …

Red blood cell contribution to hemostasis

AH Gillespie, A Doctor - Frontiers in Pediatrics, 2021 - frontiersin.org
Red Blood Cells (RBCs) have been increasingly recognized to play important roles in
hemostasis and the mechanisms by which they do so continue to be elucidated. First and …

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

DF Noubouossie, MW Henderson… - Blood, The Journal …, 2020 - ashpublications.org
Storage lesion–induced, red cell–derived microvesicles (RBC-MVs) propagate coagulation
by supporting the assembly of the prothrombinase complex. It has also been reported that …

Blood cell-derived microvesicles in hematological diseases and beyond

HT Georgatzakou, SP Fortis, EG Papageorgiou… - Biomolecules, 2022 - mdpi.com
Microvesicles or ectosomes represent a major type of extracellular vesicles that are formed
by outward budding of the plasma membrane. Typically, they are bigger than exosomes but …