Adipose tissue dysfunction, adipokines, and low-grade chronic inflammation in polycystic ovary syndrome

PM Spritzer, SB Lecke, F Satler, DM Morsch - Reproduction, 2015 - rep.bioscientifica.com
Polycystic ovary syndrome (PCOS), a complex condition that affects women of reproductive
age, is characterized by ovulatory dysfunction and androgen excess. Women with PCOS …

Gut microbiota dysbiosis in polycystic ovary syndrome: Mechanisms of progression and clinical applications

Y Sun, S Gao, C Ye, W Zhao - Frontiers in cellular and infection …, 2023 - frontiersin.org
Polycystic ovary syndrome (PCOS) is the most common endocrine diseases in women of
childbearing age that leads to menstrual disorders and infertility. The pathogenesis of PCOS …

Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease

MD Anway, C Leathers, MK Skinner - Endocrinology, 2006 - academic.oup.com
The fetal basis of adult disease is poorly understood on a molecular level and cannot be
solely attributed to genetic mutations or a single etiology. Embryonic exposure to …

Environmentally induced epigenetic transgenerational inheritance of ovarian disease

E Nilsson, G Larsen, M Manikkam… - PloS one, 2012 - journals.plos.org
The actions of environmental toxicants and relevant mixtures in promoting the epigenetic
transgenerational inheritance of ovarian disease was investigated with the use of a …

Biology of obesity: lessons from animal models of obesity

K Kanasaki, D Koya - BioMed Research International, 2011 - Wiley Online Library
Obesity is an epidemic problem in the world and is associated with several health problems,
including diabetes, cardiovascular disease, respiratory failure, muscle weakness, and …

Morbidity and medicine prescriptions in a nationwide Danish population of patients diagnosed with polycystic ovary syndrome

D Glintborg, K Hass Rubin, M Nybo… - European journal of …, 2015 - academic.oup.com
Objective The prevalence of type 2 diabetes is increased in polycystic ovary syndrome
(PCOS), but the prevalence of other diseases is not clarified. We aimed to investigate …

The association between gut microbiome and PCOS: evidence from meta-analysis and two-sample mendelian randomization

Q Min, H Geng, Q Gao, M Xu - Frontiers in Microbiology, 2023 - frontiersin.org
Background Increasing evidence from observational studies and clinical experimentation
has indicated a link between the gut microbiotas (GMs) and polycystic ovary syndrome …

Metformin treatment may increase omentin-1 levels in women with polycystic ovary syndrome

BK Tan, R Adya, S Farhatullah, J Chen, H Lehnert… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Polycystic ovary syndrome (PCOS) is associated with the metabolic syndrome.
Decreased omentin-1 levels are associated with obesity and diabetes. To study the effects of …

Hirsutism in polycystic ovary syndrome: pathophysiology and management

P Mara Spritzer, C Rocha Barone… - Current …, 2016 - ingentaconnect.com
Background: Hirsutism is defined as the presence of terminal hair with male distribution in
women, and polycystic ovary syndrome (PCOS) is the most common etiology of hirsutism …

The endocrine disruptor bisphenol A may play a role in the aetiopathogenesis of polycystic ovary syndrome in adolescent girls

L Akın, M Kendirci, F Narin, S Kurtoglu… - Acta …, 2015 - Wiley Online Library
Aim Experimental in vitro studies have shown that bisphenol A affects steroidogenesis,
folliculogenesis and ovarian morphology. The aim of this study was to investigate the role of …