Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Casting a wide net: role of perineuronal nets in neural plasticity

BA Sorg, S Berretta, JM Blacktop… - Journal of …, 2016 - Soc Neuroscience
Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain
neurons in the CNS during development and control plasticity in the adult CNS. They appear …

Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity

J Gilbert, HY Man - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …

The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders

R Fetit, RF Hillary, DJ Price, SM Lawrie - Neuroscience & Biobehavioral …, 2021 - Elsevier
Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …

The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori - International journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS …

P Wang, R Mokhtari, E Pedrosa, M Kirschenbaum… - Molecular autism, 2017 - Springer
Background CHD8 (chromodomain helicase DNA-binding protein 8), which codes for a
member of the CHD family of ATP-dependent chromatin-remodeling factors, is one of the …

Consensus paper: pathological role of the cerebellum in autism

SH Fatemi, KA Aldinger, P Ashwood, ML Bauman… - The Cerebellum, 2012 - Springer
There has been significant advancement in various aspects of scientific knowledge
concerning the role of cerebellum in the etiopathogenesis of autism. In the current …

Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses

SR Gilman, I Iossifov, D Levy, M Ronemus, M Wigler… - Neuron, 2011 - cell.com
Identification of complex molecular networks underlying common human phenotypes is a
major challenge of modern genetics. In this study, we develop a method for network-based …

Genetics of structural and functional brain changes in autism spectrum disorder

S Hashem, S Nisar, AA Bhat, SK Yadav… - Translational …, 2020 - nature.com
Autism spectrum disorder (ASD) is a neurological and developmental disorder characterized
by social impairment and restricted interactive and communicative behaviors. It may occur …

Nutritional modulation of cognitive function and mental health

N Parletta, CM Milte, BJ Meyer - The Journal of nutritional biochemistry, 2013 - Elsevier
The important role of diet in cardiometabolic health is generally well recognised; for mental
health, it is not so well understood. However, lifestyle risk factors for poor physical health are …