The effects of cocaine exposure in adolescence: Behavioural effects and neuroplastic mechanisms in experimental models
L Caffino, F Mottarlini, G Zita… - British journal of …, 2022 - Wiley Online Library
Drug addiction is a devastating disorder with a huge economic and social burden for
modern society. Although an individual may slip into drug abuse throughout his/her life …
modern society. Although an individual may slip into drug abuse throughout his/her life …
[HTML][HTML] Perinatal serotonergic manipulation shapes anhedonic and cognitive behaviors in a sex-and age-dependent manner: Identification of related biological …
MT Gallo, P Brivio, B Dolci, F Fumagalli… - Brain, Behavior, and …, 2023 - Elsevier
Poor knowledge about psychiatric disorders often results in similar diagnoses for patients
with different symptoms, thus limiting the effectiveness of the available medications. As …
with different symptoms, thus limiting the effectiveness of the available medications. As …
Cortical reorganization of the glutamate synapse in the activity‐based anorexia rat model: Impact on cognition
F Mottarlini, G Targa, G Bottan, B Tarenzi… - Journal of …, 2022 - Wiley Online Library
Patients suffering from anorexia nervosa (AN) display altered neural activity, morphological,
and functional connectivity in the fronto‐striatal circuit. In addition, hypoglutamatergic …
and functional connectivity in the fronto‐striatal circuit. In addition, hypoglutamatergic …
Transcriptional profiling of rat prefrontal cortex after acute inescapable footshock stress
Stress is a primary risk factor for psychiatric disorders such as Major Depressive Disorder
(MDD) and Post Traumatic Stress Disorder (PTSD). The response to stress involves the …
(MDD) and Post Traumatic Stress Disorder (PTSD). The response to stress involves the …
A single dose of cocaine raises SV2A density in hippocampus of adolescent rats
R Rossi, SL Bærentzen, MB Thomsen… - Acta …, 2024 - cambridge.org
ObjectiveCocaine is a highly addictive psychostimulant that affects synaptic activity with
structural and functional adaptations of neurons. The transmembrane synaptic vesicle …
structural and functional adaptations of neurons. The transmembrane synaptic vesicle …
Prenatal Fluoxetine Exposure Influences Glucocorticoid Receptor-Mediated Activity in the Prefrontal Cortex of Adolescent Rats Exposed to Acute Stress
MT Gallo, B Dolci, F Fumagalli, P Brivio… - ACS Chemical …, 2024 - ACS Publications
Any deviation from the programmed processes of brain development may modify its
formation and functions, thereby precipitating pathological conditions, which often become …
formation and functions, thereby precipitating pathological conditions, which often become …
Cognitive dysfunction and impaired neuroplasticity following repeated exposure to the synthetic cannabinoid JWH‐018 in male mice
S Bilel, E Zamberletti, L Caffino, M Tirri… - British Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Psychotic disorders have been reported in long‐term
users of synthetic cannabinoids. This study aims at investigating the long‐lasting effects of …
users of synthetic cannabinoids. This study aims at investigating the long‐lasting effects of …
[HTML][HTML] Developmental activity-based anorexia alters hippocampal non-genomic stress response and induces structural instability and spatial memory impairment in …
F Mottarlini, G Targa, B Rizzi, F Fumagalli… - Progress in Neuro …, 2024 - Elsevier
Objective Anorexia nervosa (AN) is characterized by hyperactivation of the hypothalamic-
pituitary-adrenal axis and cognitive deficits. However, little is known about the rapid non …
pituitary-adrenal axis and cognitive deficits. However, little is known about the rapid non …
Anorexia-Induced Hypoleptinemia Drives Adaptations in the JAK2/STAT3 Pathway in the Ventral and Dorsal Hippocampus of Female Rats
G Targa, F Mottarlini, B Rizzi, S Taddini, S Parolaro… - Nutrients, 2024 - mdpi.com
Leptin is an appetite-regulating adipokine that is reduced in patients with anorexia nervosa
(AN), a psychiatric disorder characterized by self-imposed starvation, and has been linked to …
(AN), a psychiatric disorder characterized by self-imposed starvation, and has been linked to …
[HTML][HTML] Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro …
L Chen, Z Liu, Z Zhao, D Du, W Pan, X Wei, J Nie… - Theranostics, 2023 - ncbi.nlm.nih.gov
Adolescent cocaine exposure (ACE) increases risk of developing psychiatric problems such
as anxiety, which may drive relapse in later life, however, its underlying molecular …
as anxiety, which may drive relapse in later life, however, its underlying molecular …