Origins of modern human ancestry

A Bergström, C Stringer, M Hajdinjak, EML Scerri… - Nature, 2021 - nature.com
New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …

Benefits and limitations of genome-wide association studies

V Tam, N Patel, M Turcotte, Y Bossé, G Paré… - Nature Reviews …, 2019 - nature.com
Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

Palaeogenomics of upper palaeolithic to neolithic European hunter-gatherers

C Posth, H Yu, A Ghalichi, H Rougier, I Crevecoeur… - Nature, 2023 - nature.com
Modern humans have populated Europe for more than 45,000 years,. Our knowledge of the
genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to …

On the limits of fitting complex models of population history to f-statistics

R Maier, P Flegontov, O Flegontova, U Işıldak… - Elife, 2023 - elifesciences.org
Our understanding of population history in deep time has been assisted by fitting admixture
graphs (AGs) to data: models that specify the ordering of population splits and mixtures …

Grey wolf genomic history reveals a dual ancestry of dogs

A Bergström, DWG Stanton, UH Taron, L Frantz… - Nature, 2022 - nature.com
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and
they remained widespread throughout the last Ice Age when many other large mammal …

[HTML][HTML] Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry

M Hajdinjak, F Mafessoni, L Skov, B Vernot, A Hübner… - Nature, 2021 - nature.com
Modern humans appeared in Europe by at least 45,000 years ago 1, 2, 3, 4, 5, but the extent
of their interactions with Neanderthals, who disappeared by about 40,000 years ago 6, and …

[HTML][HTML] Population genomics of post-glacial western Eurasia

ME Allentoft, M Sikora, A Refoyo-Martínez… - Nature, 2024 - nature.com
Western Eurasia witnessed several large-scale human migrations during the Holocene,,,–.
Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced …

Dairying, diseases and the evolution of lactase persistence in Europe

RP Evershed, G Davey Smith, M Roffet-Salque… - Nature, 2022 - nature.com
Abstract In European and many African, Middle Eastern and southern Asian populations,
lactase persistence (LP) is the most strongly selected monogenic trait to have evolved over …

The genetic history of the Southern Arc: A bridge between West Asia and Europe

I Lazaridis, S Alpaslan-Roodenberg, A Acar, A Açıkkol… - Science, 2022 - science.org
By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in
Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic …