Pathogenesis of dermatophytosis: sensing the host tissue

NM Martinez-Rossi, NTA Peres, A Rossi - Mycopathologia, 2017 - Springer
Abstract The genera Trichophyton, Microsporum, and Epidermophyton include filamentous
fungi that cause dermatophytosis, a superficial infection of the skin, stratum corneum, nail …

Reassessing the use of undecanoic acid as a therapeutic strategy for treating fungal infections

A Rossi, MP Martins, TA Bitencourt, NTA Peres… - Mycopathologia, 2021 - Springer
Treating fungal infections is challenging and frequently requires long-term courses of
antifungal drugs. Considering the limited number of existing antifungal drugs, it is crucial to …

Photorhabdus sp. ETL Antimicrobial Properties and Characterization of Its Secondary Metabolites by Gas Chromatography–Mass Spectrometry

TE Lulamba, E Green, MH Serepa-Dlamini - Life, 2021 - mdpi.com
Entomopathogenic nematodes (EPNs) are known to be highly pathogenic to insect pests,
due to their associated symbiotic bacteria, which produce virulence factors, exo-enzymes …

Variability in metabolites produced by Talaromyces pinophilus SPJ22 cultured on different substrates

OA Adelusi, S Gbashi, JA Adebiyi, R Makhuvele… - Fungal Biology and …, 2022 - Springer
Background Several metabolites released by fungal species are an essential source of
biologically active natural substances. Gas chromatography high resolution time-of-flight …

Role of pH in the pathogenesis of dermatophytoses

NM Martinez‐Rossi, GF Persinoti, NTA Peres… - Mycoses, 2012 - Wiley Online Library
The secretion of proteolytic enzymes by dermatophytes is a key factor in their invasion and
subsequent dissemination through the stratum corneum of the host. During the first stages of …

[HTML][HTML] Transcriptome-wide survey of gene expression changes and alternative splicing in Trichophyton rubrum in response to undecanoic acid

NS Mendes, TA Bitencourt, PR Sanches… - Scientific reports, 2018 - nature.com
While fatty acids are known to be toxic to dermatophytes, key physiological aspects of the
Trichophyton rubrum response to undecanoic acid (UDA), a medium chain saturated fatty …

In vitro susceptibility to antimycotic drug undecanoic acid, a medium-chain fatty acid, is nutrient-dependent in the dermatophyte Trichophyton rubrum

NTA Peres, JR Cursino-Santos, A Rossi… - World Journal of …, 2011 - Springer
The antimycotic activity of fatty acids has long been known, and their presence in human
skin and sweat appears to protect the host against superficial mycoses. Undecanoic acid is …

Bio-activity and Spectral Analysis of Gas Chromatography/Mass Spectroscopy (GCMS) Profile of Crude Spondiasmonbin Extracts

O Osuntokun, OO Ige, TO Idowu… - Journal of Analytical …, 2018 - iris.unimore.it
The purpose of this research work is to determine the biological activity and spectral
analysis of Gas chromatography/mass Spectroscopy (GC-MS) profile of crude extract of S …

Mecanismo molecular envolvido na regulação de um gene codificador de bomba de efluxo de fármacos no dermatófito Trichophyton rubrum

MER Lopes - 2021 - teses.usp.br
Dermatófitos são fungos que causam uma variedade de micoses de pele, cabelos, pelos e
unhas em animais e humanos. Eles acometem tecidos queratinizados provocando …

Análise global do perfil transcricional e splicing alternativo no dermatófito Trichophyton rubrum exposto à doses subinibitórias de ácido undecanóico

NS Mendes - 2016 - teses.usp.br
O dermatófito Trichophyton rubrum é um fungo filamentoso, antropofílico, que invade
tecidos queratinizados causando infecções superficiais e cutâneas. Algumas drogas são …