From infection to death: an overview of the pathogenesis of Visceral Leishmaniasis

CHN Costa, KP Chang, DL Costa, FVM Cunha - Pathogens, 2023 - mdpi.com
Kala-azar, also known as visceral leishmaniasis (VL), is a disease caused by Leishmania
infantum and L. donovani. Patients experience symptoms such as fever, weight loss …

The evolution of powerful yet perilous immune systems

AL Graham, EC Schrom, CJE Metcalf - Trends in immunology, 2022 - cell.com
The mammalian immune system packs serious punch against infection but can also cause
harm: for example, coronavirus disease 2019 (COVID-19) made headline news of the …

[HTML][HTML] Vaccine value profile for leishmaniasis

PM Kaye, G Matlashewski, S Mohan, E Le Rutte… - vaccine, 2023 - Elsevier
Leishmania infections are global, occurring in 98 countries and all World Health
Organization (WHO) regions with 600 million to 1 billion people at risk of infection. Visceral …

Knowledge, perceptions and practices of health students and professionals regarding leishmaniasis in Portugal: a cross-sectional study

R Rocha, C Conceição, L Gonçalves, C Maia - Parasites & Vectors, 2023 - Springer
Background Control of leishmaniasis in the Mediterranean Basin relies on the active
contributions from researchers in the fields of animal, human and environmental health. The …

Retrospective analysis of leishmaniasis in Sicily (Italy) from 2013 to 2021: One-Health impact and future control strategies

F Bruno, F Vitale, F La Russa, S Reale, GF Späth… - Microorganisms, 2022 - mdpi.com
Leishmaniasis is an important vector-borne disease that represents a serious public health
problem, including in Sicily (Italy), which is considered an endemic area. We collected …

Prevalence of asymptomatic Leishmania infection and knowledge, perceptions, and practices in blood donors in mainland Portugal

R Rocha, L Gonçalves, C Conceição, P Andrade… - Parasites & …, 2023 - Springer
Background Asymptomatic infection is the most common outcome of exposure to
Leishmania parasites. In the Mediterranean region, where Leishmania infantum is endemic …

Systematic review of treatment failure and clinical relapses in leishmaniasis from a multifactorial perspective: Clinical aspects, factors associated with the parasite and …

GA Santos, JM Sousa, AHBM Aguiar… - Tropical Medicine and …, 2023 - mdpi.com
Leishmaniasis is a disease caused by protozoa of the genus Leishmania. Treatment options
are limited, and there are frequent cases of treatment failure and clinical relapse. To …

Gene-specific sex effects on susceptibility to infectious diseases

M Lipoldová, P Demant - Frontiers in immunology, 2021 - frontiersin.org
Inflammation is an integral part of defense against most infectious diseases. These
pathogen-induced immune responses are in very many instances strongly influenced by …

Trends in the Epidemiology of Leishmaniasis in the City of Barcelona (1996–2019)

D Palma, L Mercuriali, J Figuerola… - Frontiers in Veterinary …, 2021 - frontiersin.org
Background: Leishmaniasis is a neglected zoonosis produced by 20 different flagellated
parasites of the Leishmania genus, a protozoan transmitted to humans and other vertebrates …

Clinical criteria for Mucosal Leishmaniasis diagnosis in rural South America: A systematic literature review

JM Bezemer, K Meesters, CL Naveda… - PLoS neglected …, 2022 - journals.plos.org
Background Mucosal Leishmaniasis (ML), a neglected tropical disease caused by
Leishmania parasites, impairs the quality of life of under-resourced populations in South …