Adaptation of the cardiovascular system to weightlessness: surprises, paradoxes and implications for deep space missions
P Norsk - Acta physiologica, 2020 - Wiley Online Library
Weightlessness in space induces a fluid shift from the dependent to the cephalad parts of
the body leading to distension of the cardiac chambers and an accumulation of blood in the …
the body leading to distension of the cardiac chambers and an accumulation of blood in the …
[HTML][HTML] Implementation of exercise countermeasures during spaceflight and microgravity analogue studies: developing countermeasure protocols for bedrest in older …
ET Hedge, CA Patterson, CJ Mastrandrea… - Frontiers in …, 2022 - frontiersin.org
Significant progress has been made in the development of countermeasures to attenuate
the negative consequences of prolonged exposure to microgravity on astronauts' bodies …
the negative consequences of prolonged exposure to microgravity on astronauts' bodies …
Cardiac function, structural, and electrical remodeling by microgravity exposure
MR Sy, JA Keefe, JP Sutton… - American Journal of …, 2023 - journals.physiology.org
Space medicine is key to the human exploration of outer space and pushes the boundaries
of science, technology, and medicine. Because of harsh environmental conditions related to …
of science, technology, and medicine. Because of harsh environmental conditions related to …
[HTML][HTML] Modelling large scale artery haemodynamics from the heart to the eye in response to simulated microgravity
We investigated variations in haemodynamics in response to simulated microgravity across
a semi-subject-specific three-dimensional (3D) continuous arterial network connecting the …
a semi-subject-specific three-dimensional (3D) continuous arterial network connecting the …
[HTML][HTML] A perspective on the evidence for glymphatic obstruction in spaceflight associated neuro-ocular syndrome and fatigue
GA Bateman, AR Bateman - npj Microgravity, 2024 - nature.com
Spaceflight associated neuro-ocular syndrome (SANS) alters the vision of astronauts during
long-duration spaceflights. Previously, the current authors have discussed the similarities …
long-duration spaceflights. Previously, the current authors have discussed the similarities …
Indirect measurement of absolute cardiac output during exercise in simulated altered gravity is highly dependent on the method
RS Whittle, LM Stapleton, LG Petersen… - Journal of Clinical …, 2022 - Springer
Purpose Altered gravity environments introduce cardiovascular changes that may require
continuous hemodynamic monitoring in both spaceflight and terrestrial analogs. Conditions …
continuous hemodynamic monitoring in both spaceflight and terrestrial analogs. Conditions …
Gravitational transitions increase posterior cerebral perfusion and systemic oxidative-nitrosative stress: implications for neurovascular unit integrity
The present study examined if repeated bouts of micro-and hypergravity during parabolic
flight (PF) alter structural integrity of the neurovascular unit (NVU) subsequent to free radical …
flight (PF) alter structural integrity of the neurovascular unit (NVU) subsequent to free radical …
Selective elevation in external carotid artery flow during acute gravitational transition to microgravity during parabolic flight
D Lanéelle, S Ogoh, JE Trihan… - American Journal …, 2023 - journals.physiology.org
This study sought to determine to what extent acute exposure to microgravity (0 G) and
related increases in central blood volume (CBV) during parabolic flight influence the …
related increases in central blood volume (CBV) during parabolic flight influence the …
[HTML][HTML] Inflight leg cuff test does not identify the risk for orthostatic hypotension after long-duration spaceflight
Landing day symptoms from orthostatic hypotension after prolonged spaceflight can be
debilitating, but severity of these symptoms can be unpredictable and highly individual. We …
debilitating, but severity of these symptoms can be unpredictable and highly individual. We …
Adaptation of systemic and pulmonary circulation to acute changes in gravity and body position
U Hoffmann, J Koschate… - … medicine and human …, 2019 - ingentaconnect.com
INTRODUCTION: Changes in gravity or body position provoke changes in hydrostatic
pressure in the arterial system and in venous return. Potential asymmetries between left …
pressure in the arterial system and in venous return. Potential asymmetries between left …