MusiteDeep: a deep-learning based webserver for protein post-translational modification site prediction and visualization

D Wang, D Liu, J Yuchi, F He, Y Jiang… - Nucleic Acids …, 2020 - academic.oup.com
MusiteDeep is an online resource providing a deep-learning framework for protein post-
translational modification (PTM) site prediction and visualization. The predictor only uses …

Leveraging protein dynamics to identify functional phosphorylation sites using deep learning models

F Zhu, S Yang, F Meng, Y Zheng, X Ku… - Journal of Chemical …, 2022 - ACS Publications
Accurate prediction of post-translational modifications (PTMs) is of great significance in
understanding cellular processes, by modulating protein structure and dynamics …

Research progress in protein posttranslational modification site prediction

W He, L Wei, Q Zou - Briefings in functional genomics, 2019 - academic.oup.com
Posttranslational modifications (PTMs) play an important role in regulating protein folding,
activity and function and are involved in almost all cellular processes. Identification of PTMs …

DeepPhos: prediction of protein phosphorylation sites with deep learning

F Luo, M Wang, Y Liu, XM Zhao, A Li - Bioinformatics, 2019 - academic.oup.com
Motivation Phosphorylation is the most studied post-translational modification, which is
crucial for multiple biological processes. Recently, many efforts have been taken to develop …

Using deep neural networks and biological subwords to detect protein S-sulfenylation sites

DT Do, TQT Le, NQK Le - Briefings in Bioinformatics, 2021 - academic.oup.com
Protein S-sulfenylation is one kind of crucial post-translational modifications (PTMs) in which
the hydroxyl group covalently binds to the thiol of cysteine. Some recent studies have shown …

TargetCPP: accurate prediction of cell-penetrating peptides from optimized multi-scale features using gradient boost decision tree

M Arif, S Ahmad, F Ali, G Fang, M Li, DJ Yu - Journal of computer-aided …, 2020 - Springer
Cell-penetrating peptides (CPPs) are short length permeable proteins have emerged as
drugs delivery tool of therapeutic agents including genetic materials and macromolecules …

MIND-S is a deep-learning prediction model for elucidating protein post-translational modifications in human diseases

Y Yan, JY Jiang, M Fu, D Wang, AR Pelletier… - Cell reports …, 2023 - cell.com
We present a deep-learning-based platform, MIND-S, for protein post-translational
modification (PTM) predictions. MIND-S employs a multi-head attention and graph neural …

Deep Learning–Based Advances In Protein Posttranslational Modification Site and Protein Cleavage Prediction

SC Pakhrin, S Pokharel, H Saigo, DB Kc - Computational Methods for …, 2022 - Springer
Posttranslational modification (PTM) is a ubiquitous phenomenon in both eukaryotes and
prokaryotes which gives rise to enormous proteomic diversity. PTM mostly comes in two …

Exploring the potential of 3D Zernike descriptors and SVM for protein–protein interface prediction

S Daberdaku, C Ferrari - BMC bioinformatics, 2018 - Springer
Background The correct determination of protein–protein interaction interfaces is important
for understanding disease mechanisms and for rational drug design. To date, several …

Accurately predicting glutarylation sites using sequential bi-peptide-based evolutionary features

ME Arafat, MW Ahmad, SM Shovan, A Dehzangi… - Genes, 2020 - mdpi.com
Post Translational Modification (PTM) is defined as the alteration of protein sequence upon
interaction with different macromolecules after the translation process. Glutarylation is …