Autophagy and the hallmarks of aging

S Kaushik, I Tasset, E Arias, O Pampliega… - Ageing research …, 2021 - Elsevier
Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …

Mitochondria, the gut microbiome and ROS

JWO Ballard, SG Towarnicki - Cellular signalling, 2020 - Elsevier
In this review, we discuss the connections between mitochondria and the gut microbiome
provided by reactive oxygen species (ROS). We examine the mitochondrion as an …

[图书][B] Encyclopedia of gerontology and population aging

D Gu, ME Dupre - 2021 - Springer
Diet is the only known intervention which has been conclusively shown to extend life span. It
can be argued the key role diet has to play in the aging process came to prominence as a …

Drosophila melanogaster as a Versatile Model Organism in Food and Nutrition Research

S Staats, K Lüersen, AE Wagner… - Journal of agricultural …, 2018 - ACS Publications
Drosophila melanogaster has been widely used in the biological sciences as a model
organism. Drosophila has a relatively short life span of 60–80 days, which makes it attractive …

Exploring ayurvedic knowledge on food and health for providing innovative solutions to contemporary healthcare

U Payyappallimana… - Frontiers in public health, 2016 - frontiersin.org
Ayurveda, a traditional system of medicine that originated over three millennia ago in the
South Asian region, offers extensive insights about food and health based on certain unique …

[HTML][HTML] Gender-specific effects of pro-longevity interventions in Drosophila

O Lushchak, O Strilbytska, KB Storey - Mechanisms of ageing and …, 2023 - Elsevier
Sex differences in lifespan are well recognized in the majority of animal species. For
example, in male versus female Drosophila melanogaster there are significant differences in …

Drosophila melanogaster “a potential model organism” for identification of pharmacological properties of plants/plant-derived components

K Panchal, AK Tiwari - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Plants/plant-derived components have been used from ancient times to treat/cure several
human diseases. Plants and their parts possess several chemical components that play the …

Honeysuckle extract (Lonicera pallasii L.) exerts antioxidant properties and extends the lifespan and healthspan of Drosophila melanogaster

D Golubev, N Zemskaya, O Shevchenko… - Biogerontology, 2022 - Springer
Abstract Honeysuckle Lonicera pallasii (Lonicera caerulea L.) is an excellent source of
anthocyanins which have a number of health-promoting properties mainly associated with …

Dietary Resveratrol Does Not Affect Life Span, Body Composition, Stress Response, and Longevity-Related Gene Expression in Drosophila melanogaster

S Staats, AE Wagner, B Kowalewski, FT Rieck… - International journal of …, 2018 - mdpi.com
In this study, we tested the effect of the stilbene resveratrol on life span, body composition,
locomotor activity, stress response, and the expression of genes encoding proteins centrally …

Pomegranate activates TFEB to promote autophagy-lysosomal fitness and mitophagy

S Tan, CY Yu, ZW Sim, ZS Low, B Lee, F See, N Min… - Scientific reports, 2019 - nature.com
Mitochondrial dysfunction underscores aging and diseases. Mitophagy (mito chondria+ auto
phagy) is a quality control pathway that preserves mitochondrial health by targeting …