The devastating effects of sleep deprivation on memory: lessons from rodent models
P Chen, W Ban, W Wang, Y You, Z Yang - Clocks & Sleep, 2023 - mdpi.com
In this narrative review article, we discuss the role of sleep deprivation (SD) in memory
processing in rodent models. Numerous studies have examined the effects of SD on …
processing in rodent models. Numerous studies have examined the effects of SD on …
Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer's disease
Failed proteostasis is a well-documented feature of Alzheimer's disease, particularly,
reduced protein degradation and clearance. However, the contribution of failed proteostasis …
reduced protein degradation and clearance. However, the contribution of failed proteostasis …
[HTML][HTML] Impact of sleep disturbances on neurodegeneration: Insight from studies in animal models
JE Owen, SC Veasey - Neurobiology of disease, 2020 - Elsevier
Chronic short sleep or extended wake periods are commonly observed in most
industrialized countries. Previously neurobehavioral impairment following sleep loss was …
industrialized countries. Previously neurobehavioral impairment following sleep loss was …
The effect of curcumin differs on individual cognitive domains across different patient populations: a systematic review and meta-analysis
Curcumin is a polyphenol with strong antioxidant and anti-inflammatory effects that has been
shown to be effective in ameliorating cognitive decline in animal studies. However, its …
shown to be effective in ameliorating cognitive decline in animal studies. However, its …
[HTML][HTML] REM sleep deprivation induced by the modified multi-platform method has detrimental effects on memory: A systematic review and meta-analysis
H Diao, Y Li, W Sun, J Zhang, M Wang, Y Chen… - Behavioural Brain …, 2023 - Elsevier
The modified multi-platform method (MMPM) is used to induce animal models of paradoxical
sleep deprivation and impairs memory in rodents. However, variations in MMPM protocols …
sleep deprivation and impairs memory in rodents. However, variations in MMPM protocols …
Ginsenoside Rg3 modulates spatial memory and fear memory extinction by the HPA axis and BDNF-TrkB pathway in a rat post-traumatic stress disorder
B Sur, B Lee - Journal of Natural Medicines, 2022 - Springer
Post-traumatic stress disorder (PTSD) is a serious mental disorder that can develop after
exposure to extreme stress. Korean red ginseng, whose major active component is …
exposure to extreme stress. Korean red ginseng, whose major active component is …
Restorative effects of curcumin on sleep-deprivation induced memory impairments and structural changes of the hippocampus in a rat model
The present study examined the consequences of rapid eye-movement sleep-deprivation
(REM-SD) with or without curcumin treatment. The outcome measures comprised …
(REM-SD) with or without curcumin treatment. The outcome measures comprised …
A New Perspective on the Treatment of Alzheimer's Disease and Sleep Deprivation‐Related Consequences: Can Curcumin Help?
Sleep disturbances, as well as sleep‐wake rhythm disorders, are characteristic symptoms of
Alzheimer's disease (AD) that may head the other clinical signs of this neurodegenerative …
Alzheimer's disease (AD) that may head the other clinical signs of this neurodegenerative …
Curcumin prevents neuronal loss and structural changes in the superior cervical (sympathetic) ganglion induced by chronic sleep deprivation, in the rat model
Background In modern societies, sleep deprivation is a serious health problem. This
problem could be induced by a variety of reasons, including lifestyle habits or neurological …
problem could be induced by a variety of reasons, including lifestyle habits or neurological …
Alzheimer's disease, sleep disordered breathing, and microglia: puzzling out a common link
TK Ulland, AC Ewald, AO Knutson, KM Marino… - Cells, 2021 - mdpi.com
Sleep Disordered Breathing (SDB) and Alzheimer's Disease (AD) are strongly associated
clinically, but it is unknown if they are mechanistically associated. Here, we review data …
clinically, but it is unknown if they are mechanistically associated. Here, we review data …