Gene selection of microarray data using heatmap analysis and graph neural network

SK Pati, A Banerjee, S Manna - Applied Soft Computing, 2023 - Elsevier
It is not feasible to investigate the whole genes at a microscopic level for disease
classification in Genomics. It might take substantial time to execute any meaningful analysis …

Synthetic lethality and the minimal genome size problem

S Rahiminejad, B De Sanctis, P Pevzner, A Mushegian - Msphere, 2024 - journals.asm.org
Gene knockout studies suggest that~ 300 genes in a bacterial genome and~ 1,100 genes in
a yeast genome cannot be deleted without loss of viability. These single-gene knockout …

Constructing gene similarity networks using co-occurrence probabilities

G Mirzaei - BMC genomics, 2023 - Springer
Gene similarity networks play important role in unraveling the intricate associations within
diverse cancer types. Conventionally, gauging the similarity between genes has been …

[PDF][PDF] A Stochastic Framework to Fuzzy Environments Through Case-based Reasoning and the Inverse Problem Methodology: An Investigation of Financial Bubbles

F Ekpenyong - 2021 - cris.brighton.ac.uk
This thesis presents an approach to support the identification and potential investigation of
abnormal asset performance in traded securities, often popularised as 'financial bubbles'. It …

[PDF][PDF] Binarized single cell RNA sequencing data clustering

J Theunisz - 2023 - repository.tudelft.nl
Single-cell RNA sequencing data clustering is a valuable technique for demonstrating cell-
tocell heterogeneity and revealing cell dynamics within and amongst groups. Large up …

Mathematical tools for analysis of genome function, linkage disequilibrium structure and disease gene prediction

N Vergara Lope Gracia - 2021 - eprints.soton.ac.uk
Next-generation sequencing (NGS) help to identify disease-causing genes underlying any
given monogenic or complex disease. Concurrently, mathematical tools and statistical …

Making data-driven hypotheses for gene functions by integrating dependency, expression, and literature data

MD Hirschey - bioRxiv, 2020 - biorxiv.org
Identifying the key functions of human genes is a major biomedical research goal. While
some genes are well-studied, most human genes we know little about. New tools in data …

Confidence in protein interaction networks

LV Bozhilova - 2019 - ora.ox.ac.uk
Protein interaction networks are a commonly used tool in bioinformatics, eg for the purposes
of gene function prediction or drug target identification. They are built from often …