Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …

The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is a
key intracellular mediator of a variety of metabolically relevant hormones and cytokines …

Fibro-adipogenic progenitors (FAPs) are typically activated in response to muscle injury, and
establish functional interactions with inflammatory and muscle stem cells (MuSCs) to …

Purpose Quality of life is a key component of cancer care; however, the factors that
determine quality of life are not well understood. The aim of this study was to examine the …

Cachexia is a debilitating syndrome characterized by involuntary muscle wasting that is
triggered at the late stage of many cancers. While the multifactorial nature of this syndrome …

Weight loss due to skeletal muscle atrophy in patients with chronic pulmonary disease is
negatively correlated with clinical outcome. Pulmonary fibrosis is a chronic and progressive …

Summary yki-induced gut tumors in Drosophila are associated with host wasting, including
muscle dysfunction, lipid loss, and hyperglycemia, a condition reminiscent of human cancer …

ABSTRACT Introduction Sesquiterpene lactones (SLs) are one of the most diverse bioactive
secondary metabolites found in plants and exhibit a broad range of therapeutic properties …

Progressive muscle weakness and degeneration characterize Duchenne muscular
dystrophy (DMD), a lethal, x-linked neuromuscular disorder that affects 1 in 5,000 boys. Loss …

Peripheral nerve injury is common, and can lead to skeletal muscle atrophy and dysfunction.
However, the underlying molecular mechanisms are not fully understood. The transcription …