The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating
consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome …

Basement membrane laminins (LNs) have been shown to modulate cellular phenotypes and
differentiation both in vitro and during organogenesis in vivo. At least 16 laminin isoforms …

The flavivirus genus contains several clinically important pathogens that account for
tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can …

Congenital Zika virus (ZIKV) infection results in neurodevelopmental deficits in up to 14% of
infants born to ZIKV-infected mothers. Neutralizing antibodies are a critical component of …

Zika virus (ZIKV) is an Aedes-mosquito-borne flavivirus that causes debilitating congenital
and developmental disorders. Improved understanding of ZIKV pathogenesis could assist …

Experimental increase of CpG dinucleotides in an RNA virus genome impairs infection
providing a promising approach for vaccine development. While CpG recoding is an …

The Zika virus (ZIKV) epidemic in the Americas was alarming because of its link with
microcephaly in neonates and Guillain-Barré syndrome in adults. The unusual pathologies …

Introduction: With the increasing number of vaccines and vaccine-preventable diseases, the
pressure to generate multi-valent and multi-pathogen vaccines grows. Combining individual …

The four dengue viruses (DENVs) have evolved multiple mechanisms to ensure its survival.
Among these mechanisms is the ability to regulate its replication rate, which may contribute …

Preexisting immunity to Zika virus (ZIKV) or dengue virus (DENV) may alter the course of
their infection, and here we use robust mouse models to examine pathological outcomes …