The impact of genetic research on our understanding of normal cognitive ageing: 1995 to 2009
A Payton - Neuropsychology review, 2009 - Springer
Identifying the risk factors for individual differences in age-related cognitive ability and
decline is amongst the greatest challenges facing the healthcare of older people. Cognitive …
decline is amongst the greatest challenges facing the healthcare of older people. Cognitive …
The CREB1-BDNF-NTRK2 pathway in depression: multiple gene-cognition-environment interactions
BACKGROUND: The neuroplastic pathway, which includes cyclic adenosine
monophosphate response element-binding protein 1 (CREB1), brain-derived neurotrophic …
monophosphate response element-binding protein 1 (CREB1), brain-derived neurotrophic …
BDNF Val66Met and cognition: all, none, or some? A meta‐analysis of the genetic association
SD Mandelman, EL Grigorenko - Genes, Brain and Behavior, 2012 - Wiley Online Library
The Val66Met, G196A (rs6265) polymorphism in the brain‐derived neurotrophic factor gene,
BDNF, located at 11p13, has been associated with a wide range of cognitive functions. Yet …
BDNF, located at 11p13, has been associated with a wide range of cognitive functions. Yet …
Behavioural genetics of the serotonin transporter
K Haddley, VJ Bubb, G Breen… - Behavioral …, 2012 - Springer
The serotonin transporter is a key regulator of the bioavailability of serotonin and therefore
any modulation in the expression or action of the transporter would be expected to have …
any modulation in the expression or action of the transporter would be expected to have …
Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults
T Richter-Schmidinger, P Alexopoulos, M Horn… - Journal of neural …, 2011 - Springer
Unravelling the impact of genetic variants on clinical phenotypes is a challenging task.
Apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) play an important …
Apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) play an important …
Characterization of a REST-regulated internal promoter in the schizophrenia genome-wide associated gene MIR137
MIR137 has been identified as a candidate gene for schizophrenia from genome-wide
association studies via association with an intronic single nucleotide polymorphism (SNP) …
association studies via association with an intronic single nucleotide polymorphism (SNP) …
Ebbinghaus Revisited: Influences of the BDNF Val66Met Polymorphism on Backward Serial Recall Are Modulated by Human Aging
The brain-derived neurotrophic factor (BDNF) plays an important role in activity-dependent
synaptic plasticity, which underlies learning and memory. In a sample of 948 younger and …
synaptic plasticity, which underlies learning and memory. In a sample of 948 younger and …
An Evaluation of a SVA Retrotransposon in the FUS Promoter as a Transcriptional Regulator and Its Association to ALS
AL Savage, TP Wilm, K Khursheed, A Shatunov… - PLoS …, 2014 - journals.plos.org
Genetic mutations of FUS have been linked to many diseases including Amyotrophic Lateral
Sclerosis (ALS) and Frontotemporal Lobar Degeneration. A primate specific and …
Sclerosis (ALS) and Frontotemporal Lobar Degeneration. A primate specific and …
Role of RET genetic variants in MEN2-associated pheochromocytoma
DR Siqueira, L Ceolin, CV Ferreira… - European journal of …, 2014 - academic.oup.com
Background RET polymorphisms have been involved in the clinical presentation and
prognosis of multiple endocrine neoplasia type 2 (MEN2)-associated medullary thyroid …
prognosis of multiple endocrine neoplasia type 2 (MEN2)-associated medullary thyroid …
REST, a master regulator of neurogenesis, evolved under strong positive selection in humans and in non human primates
The transcriptional repressor REST regulates many neuronal genes by binding RE1 motifs.
About one third of human RE1s are recently evolved and specific to primates. As changes in …
About one third of human RE1s are recently evolved and specific to primates. As changes in …