The global spread of multidrug-resistant organisms has led to an increase in urinary tract
infections (UTIs) in children that are difficult to treat. This review explores the current …

Carbapenem-resistant organisms (CRO) are a major global public health threat.
Enterobacterales hydrolyze almost all β-lactams through carbapenemase production …

The mechanism of resistance in carbapenem-resistant Enterobacteriaceae (CRE) has
therapeutic implications. We comprehensively characterized emerging mechanisms of …

Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging global public health
threat. Infections due to CRE are associated with significant morbidity and mortality. Few …

Carbapenem-resistant Enterobacteriaceae (CRE) are a concern for health care in the United
States but remain relatively uncommon in California. We describe the phenotype, clonality …

Since the first New Delhi metallo-beta-lactamase (NDM) report in 2009, NDM has spread
globally causing various types of infections. NDM-positive organisms produce in vitro …

Objective: To review the origin, diagnosis, treatment and public health concern of New Delhi
metallo-β-lactamase (NDM)-producing bacteria. Data Sources: We searched database for …

The evolution of antimicrobial-resistant Gram-negative pathogens is a substantial menace to
public health sectors, notably in developing countries because of the scarcity of healthcare …

The emergence and dissemination of carbapenem resistance among Enterobacteriaceae,
especially Klebsiella pneumoniae, constitute a serious threat to public health, since …

Background. Emergence of extensively drug-resistant (XDR) bacteria has forced clinicians
to use off-label antimicrobial agents such as tigecycline. We present our experience on …