Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex

T Chartrand, R Dalley, J Close, NA Goriounova… - Science, 2023 - science.org
Neocortical layer 1 (L1) is a site of convergence between pyramidal-neuron dendrites and
feedback axons where local inhibitory signaling can profoundly shape cortical processing …

Transcriptomic cell-type specificity of local cortical circuits

M Patiño, MA Rossa, WN Lagos, NS Patne… - Neuron, 2024 - cell.com
Complex neocortical functions rely on networks of diverse excitatory and inhibitory neurons.
While local connectivity rules between major neuronal subclasses have been established …

Temporal disparity of action potentials triggered in axon initial segments and distal axons in the neocortex

M Rózsa, M Tóth, G Oláh, J Baka, R Lákovics… - Science …, 2023 - science.org
Neural population activity determines the timing of synaptic inputs, which arrive to dendrites,
cell bodies, and axon initial segments (AISs) of cortical neurons. Action potential initiation in …

A combinatory genetic strategy for targeting neurogliaform neurons in the mouse basolateral amygdala

A Ozsvár, MC Sieburg, MD Sietam, WH Hou… - Frontiers in Cellular …, 2024 - frontiersin.org
The mouse basolateral amygdala (BLA) contains various GABAergic interneuron
subpopulations, which have distinctive roles in the neuronal microcircuit controlling …

Morpho-electric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex

T Chartrand, R Dalley, J Close, NA Goriounova… - bioRxiv, 2022 - biorxiv.org
Abstract Neocortical layer 1 (L1) is a site of convergence between pyramidal neuron
dendrites and feedback axons where local inhibitory signaling can profoundly shape cortical …

Developmental emergence of cortical neurogliaform cell diversity

L Gomez, C Cadilhac, J Prados, N Mule… - …, 2023 - journals.biologists.com
GABAergic interneurons are key regulators of cortical circuit function. Among the dozens of
reported transcriptionally distinct subtypes of cortical interneurons, neurogliaform cells …

[PDF][PDF] VU Research Portal

T Chartrand, R Dalley, J Close, NA Goriounova… - research.vu.nl
RESULTS: We leveraged single-cell transcriptomics to define neuronal cell types in human
and mouse L1 and to quantitatively identify homologous subclasses across species …

GABAergic cell types and modulation of GABAergic synaptic transmission by group III metabotropic glutamate receptors in the human neocortex

IP Lukács - 2021 - ora.ox.ac.uk
The neocortex is a layered, modular structure on the surface of the mammalian brain, which
together with other brain structures supports behavioural adaptation to the changing …