GPR56: An adhesion GPCR involved in brain development, neurological disorders and cancer

RA Ganesh, K Venkataraman, R Sirdeshmukh - Brain research, 2020 - Elsevier
GPR56/ADGRG1 is a member of the adhesion G-protein coupled receptor (aGPCR) family
and one of the important players in the normal development of the brain. It plays a pivotal …

[HTML][HTML] Estrogen enhances human osteoblast survival and function via promotion of autophagy

S Gavali, MK Gupta, B Daswani, MR Wani… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Estrogen increases bone formation by promoting mineralization and prolonging the lifespan
of osteoblasts. To understand the underlying molecular mechanism/s, we identified estrogen …

Algal extracts based biogenic synthesis of reduced graphene oxides (rGO) with enhanced heavy metals adsorption capability

S Ahmad, A Ahmad, S Khan, S Ahmad, I Khan… - Journal of Industrial and …, 2019 - Elsevier
Efficient reduction of GO was performed, using cellular extracts of three algal strains. The
rGO were characterized by SEM, TEM, UV-Visible spectroscopy, XRD, FTIR, Raman …

Plasma-derived candidate biomarkers for detection of gallbladder carcinoma

R Priya, V Jain, J Akhtar, G Chauhan, P Sakhuja… - Scientific Reports, 2021 - nature.com
Gallbladder carcinoma (GBC) is a major cancer of the gastrointestinal tract with poor
prognosis. Reliable and affordable biomarker-based assays with high sensitivity and …

Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion

MK Gupta, RV Polisetty, R Sharma, RA Ganesh… - Scientific reports, 2019 - nature.com
We have studied differentially regulated nuclear proteome of the clinical tissue specimens of
glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using …

[HTML][HTML] LYN, a key mediator in estrogen-dependent suppression of osteoclast differentiation, survival, and function

S Gavali, MK Gupta, B Daswani, MR Wani… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Estrogen insufficiency at menopause cause accelerated bone loss due to unwarranted
differentiation and function of osteoclasts. Unraveling the underlying mechanism/s may …

Multi-omics analysis of glioblastoma and glioblastoma cell line: molecular insights into the functional role of GPR56 and TG2 in mesenchymal transition

RA Ganesh, P Sonpatki, D Naik, AE John… - Frontiers in …, 2022 - frontiersin.org
G protein-coupled receptor 56 (GPR56/ADGRG1) is an adhesion GPCR with an essential
role in brain development and cancer. Elevated expression of GPR56 was observed in the …

Quantitative proteomic analysis of GnRH agonist treated GBM cell line LN229 revealed regulatory proteins inhibiting cancer cell proliferation

PH Tripathi, J Akhtar, J Arora, RK Saran, N Mishra… - BMC cancer, 2022 - Springer
Abstract Background Gonadotropin-releasing hormone (GnRH) receptor, a rhodopsin-like G-
protein coupled receptor (GPCR) family member involved in GnRH signaling, is reported to …

Membrane proteome of invasive retinoblastoma: differential proteins and biomarkers

R Danda, K Ganapathy, G Sathe… - PROTEOMICS …, 2018 - Wiley Online Library
Purpose: Retinoblastoma (RB) is a pediatric ocular cancer which is caused due to the
aberrations in the RB1 gene. The changes in the membrane proteomics would help in …

Green and catalyst-free synthesis of aminoanthraquinone derivatives in solvent-free conditions

A Sardashti-Birjandi, E Mollashahi… - Research on Chemical …, 2021 - Springer
In this study, new derivatives of aminoanthraquinone have been synthesized via one-pot
three-component condensation reaction of 1-and 2-amino anthraquinones, triethyl …