Ethnopharmacological relevance Catharanthus roseus (L.) G. Don is a well known
medicinal plant belonging to family Apocynaceae that have been traditionally used as …

Indole alkaloids have attracted attention because of their therapeutic properties, being anti-
inflammatory, antinociceptive, antitumoural, antioxidant and antimicrobial. These …

Background Plant-derived exosomes-like nanovesicles (PDENs) have been found to be
advantageous in disease treatment and drug delivery, but research on their biogenesis …

Accelerated emergence of drug-resistant pathogenic microbes, their unbeatable virulence
and a gradual loss of efficacy of currently used antimicrobial agents over the last decade …

By the end of the twentieth century, the interest in natural compounds as probable sources of
drugs has declined and was replaced by other strategies such as molecular target-based …

The family Apocynaceae is one of the largest and important families in angiosperm. Several
members of this family have medicinal properties and have been in the treatment of various …

Catharanthus roseus (C. roseus) is an important medicinal plant distributed in many
countries. It has attracted increasing attention due to it being shown to possess a range of …

Cancer occurrence is rapidly increasing all over the world, including in developing
countries. The current trend in cancer management requires the use of herbal remedies …

Vindogentianine, a new indole alkaloid together with six known alkaloids, vindoline,
vindolidine, vindolicine, vindolinine, perivine and serpentine were isolated from leaf extract …

Abstract Background Catharanthus roseus (L.) G. Don consists of a range of dimeric indole
alkaloids with significant antitumor activities. These alkaloids have been found to possess …