Tag thy neighbour: nanometre-scale insights into kinetoplastid parasites with proximity dependent biotinylation

V Geoghegan, JC Mottram, NG Jones - Frontiers in cellular and …, 2022 - frontiersin.org
Proximity labelling is a powerful and rapidly developing technology for exploring the
interaction space and molecular environment of a protein of interest at the nanometre scale …

Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease

A Pezza, LE Tavernelli, VL Alonso… - ACS infectious …, 2022 - ACS Publications
Trypanosoma cruzi is a unicellular parasite that causes Chagas disease, which is endemic
in the American continent but also worldwide, distributed by migratory movements. A striking …

Genomic occupancy of the bromodomain protein Bdf3 is dynamic during differentiation of African trypanosomes from bloodstream to procyclic forms

E Ashby, L Paddock, HL Betts, J Liao, G Miller, A Porter… - Msphere, 2022 - Am Soc Microbiol
Trypanosoma brucei, the causative agent of human and animal African trypanosomiasis,
cycles between a mammalian host and a tsetse fly vector. The parasite undergoes huge …

RNA-binding proteins required for differentiation and infectivity in Leishmania mexicana parasites

E Parry - 2022 - etheses.whiterose.ac.uk
Leishmania species are single celled kinetoplastid parasites and the causative agents of the
neglected tropical disease, leishmaniasis. Leishmania parasites differentiate between non …