In glaucoma, lowered intraocular pressure (IOP) confers neuroprotection. Elevated IOP
characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased …

The trabecular meshwork (TM) is located in the anterior segment of the eye and is
responsible for regulating the outflow of aqueous humor. Increased resistance to aqueous …

Glaucoma is a family of optic neuropathies which cause irreversible but potentially
preventable vision loss. Vision loss in most forms of glaucoma is related to elevated IOP with …

With the combined purpose of facilitating useful vision over a lifetime, a number of ocular
cells have evolved specialized features not found elsewhere in the body. The trabecular …

Transforming growth factor-β2 (TGF-β2) is found in increasing amounts in aqueous humor
and reactive optic nerve astrocytes of patients with primary open-angle glaucoma (POAG), a …

Background Glaucoma is a group of optic neuropathies in which damage to the optic nerve
results in a distinctive pattern of irreversible vision loss. Elevations in the intraocular …

RNA interference (RNAi) can be used to inhibit the expression of specific genes in vitro and
in vivo, thereby providing an extremely useful tool for investigating gene function. Progress …

The second annual ARVO/Pfizer Ophthalmic Research Insti-tute conference was held Friday
and Saturday, April 28 and 29, 2006, at the Fort Lauderdale Grande Hotel and Yacht Club …

Elevated intraocular pressure (IOP) is the principal risk factor for glaucoma and results from
excessive impedance of the fluid outflow from the eye. This abnormality likely originates from …

▪ Abstract Glaucoma describes a group of diseases that kill retinal ganglion cells. There are
different types of glaucoma, and each appears to be genetically heterogeneous. Different …