AMPA receptor trafficking at excitatory synapses

DS Bredt, RA Nicoll - Neuron, 2003 - cell.com
Excitatory synapses in the CNS release glutamate, which acts primarily on two types of
ionotropic receptors: AMPA receptors and NMDA receptors. AMPA receptors mediate the …

Glutamate receptors in the mammalian central nervous system

S Ozawa, H Kamiya, K Tsuzuki - Progress in neurobiology, 1998 - Elsevier
Glutamate receptors (GluRs) mediate most of the excitatory neurotransmission in the
mammalian central nervous system (CNS). In addition, they are involved in plastic changes …

[HTML][HTML] Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit

KW Roche, RJ O'Brien, AL Mammen, J Bernhardt… - Neuron, 1996 - cell.com
We have characterized the phosphorylation of the glutamate receptor subunit GluR1, using
biochemical and electrophysiological techniques. GluR1 is phosphorylated on multiple sites …

Molecular biology of mammalian plasma membrane amino acid transporters

M Palacín, R Estévez, J Bertran… - Physiological …, 1998 - journals.physiology.org
Palacı́n, Manuel, Raúl Estévez, Joan Bertran, and Antonio Zorzano. Molecular Biology of
Mammalian Plasma Membrane Amino Acid Transporters. Physiol. Rev. 78: 969–1054, 1998 …

Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block

D Bowie, ML Mayer - Neuron, 1995 - cell.com
Ca=*-permeable glutamate receptors assembled from subunits containing a GLN residue at
the RNA editing site in membrane domain 2 show strong inward rectification. In HEK 293 …

Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases

M Niethammer, E Kim, M Sheng - Journal of Neuroscience, 1996 - Soc Neuroscience
Selective concentration and anchoring of ionotropic receptors at the synapse is essential for
neuronal signaling. Little is known about the molecules that mediate receptor clustering in …

Interactions of polyamines with ion channels

K Williams - Biochemical Journal, 1997 - portlandpress.com
Endogenous polyamines, in particular spermine, have been found to cause block and
modulation of a number of types of ion channel. Intracellular spermine is responsible for …

Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit

B Laube, H Hirai, M Sturgess, H Betz, J Kuhse - Neuron, 1997 - cell.com
NMDA receptors require both L-glutamate and the coagonist glycine for efficient channel
activation. The glycine binding site of these heteromeric receptor proteins is formed by …

[图书][B] The physiology of excitable cells

DJ Aidley - 1998 - books.google.com
This book provides the reader with an account of some of the experimental evidence on
which our present knowledge is based. The third edition of this highly successful book has …

Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging

EK Michaelis - Progress in neurobiology, 1998 - Elsevier
Forty years of research into the function of l-glutamic acid as a neurotransmitter in the
vertebrate central nervous system (CNS) have uncovered a tremendous complexity in the …