Juvenile idiopathic arthritis is a broad term that describes a clinically heterogeneous group
of arthritides of unknown cause, which begin before 16 years of age. This term …

Autoimmune diseases (ADs) represent a heterogenous group of complex diseases with
increasing incidence in Western countries and are a major cause of morbidity …

In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune
diseases (ADs) were published, while an international coordinated clinical programme was …

Context Stem cell therapy is rapidly developing and has generated excitement and promise
as well as confusion and at times contradictory results in the lay and scientific literature …

ContextThe treatment of juvenile idiopathic arthritis (JIA) has changed markedly in the last
15 years. Many children with JIA are not treated by pediatric rheumatologists. ObjectiveTo …

Juvenile idiopathic arthritis (JIA), a term referring to a group of disorders characterized by
chronic arthritis, is the most common chronic rheumatic illness in children and is a significant …

Stem cells are a relevant source of information about cellular differentiation, molecular
processes and tissue homeostasis, but also one of the most putative biological tools to treat …

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Despite a rapidly accumulating clinical experience with autologous stem cell transplantation
(ASCT) as a treatment for severe refractory autoimmune disease, data on the mechanisms …

Systemic juvenile idiopathic arthritis (sJIA) is generally seen as the most severe category of
JIA. These categories are distinct in their pathobiology, disease course and specific …