[HTML][HTML] IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies
A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …
mediating innate and adaptive immunity and multiple physiological processes, including …
Inflammasomes: their role in normal and complicated pregnancies
Inflammasomes are cytoplasmic multiprotein complexes that coordinate inflammatory
responses, including those that take place during pregnancy. Inflammasomes and their …
responses, including those that take place during pregnancy. Inflammasomes and their …
[HTML][HTML] Single cell transcriptional signatures of the human placenta in term and preterm parturition
More than 135 million births occur each year; yet, the molecular underpinnings of human
parturition in gestational tissues, and in particular the placenta, are still poorly understood …
parturition in gestational tissues, and in particular the placenta, are still poorly understood …
[HTML][HTML] Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques
Introduction: The objectives of this study were: 1) to determine the amniotic fluid (AF)
microbiology of patients with the diagnosis of clinical chorioamnionitis at term using both …
microbiology of patients with the diagnosis of clinical chorioamnionitis at term using both …
[HTML][HTML] A single-cell atlas of the myometrium in human parturition
Parturition is a well-orchestrated process characterized by increased uterine contractility,
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …
Sterile intra-amniotic inflammation in asymptomatic patients with a sonographic short cervix: prevalence and clinical significance
Objective: To determine the frequency and clinical significance of sterile and microbial-
associated intra-amniotic inflammation in asymptomatic patients with a sonographic short …
associated intra-amniotic inflammation in asymptomatic patients with a sonographic short …
Uterine overdistention induces preterm labor mediated by inflammation: observations in pregnant women and nonhuman primates
KMA Waldorf, N Singh, AR Mohan, RC Young… - American journal of …, 2015 - Elsevier
Objective Uterine overdistention is thought to induce preterm labor in women with twin and
multiple pregnancies, but the pathophysiology remains unclear. We investigated for the first …
multiple pregnancies, but the pathophysiology remains unclear. We investigated for the first …
Damage-associated molecular patterns (DAMPs) in preterm labor with intact membranes and preterm PROM: a study of the alarmin HMGB1
R Romero, T Chaiworapongsa… - The journal of …, 2011 - Taylor & Francis
Objective. Preterm parturition is a syndrome caused by multiple etiologies. Although intra-
amniotic infection is causally linked with intrauterine inflammation and the onset of preterm …
amniotic infection is causally linked with intrauterine inflammation and the onset of preterm …
Progesterone receptor-A and-B have opposite effects on proinflammatory gene expression in human myometrial cells: implications for progesterone actions in human …
H Tan, L Yi, NS Rote, WW Hurd… - The Journal of Clinical …, 2012 - academic.oup.com
Context: Progesterone promotes uterine relaxation during pregnancy and its withdrawal
induces labor. Progesterone withdrawal in human parturition is mediated in part by changes …
induces labor. Progesterone withdrawal in human parturition is mediated in part by changes …
Physiologic uterine inflammation and labor onset: integration of endocrine and mechanical signals
O Shynlova, YH Lee, K Srikhajon… - Reproductive …, 2013 - journals.sagepub.com
The mechanisms underlying the preparation of the uterus for labor are not fully understood.
Our previous studies have shown that during pregnancy, the uterine muscle (myometrium) …
Our previous studies have shown that during pregnancy, the uterine muscle (myometrium) …